Evidence map›Paper›PMID 35607701›Full record

ArticleOpen forum infectious diseases2022

Pathogen Species Is Associated With Mortality in Nosocomial Bloodstream Infection in Patients With COVID-19.

Juan Gago, Thomas D Filardo, Sarah Conderino, Samuel J Magaziner, Yanina Dubrovskaya, Kenneth Inglima, Eduardo Iturrate, Alejandro Pironti, Jonas Schluter, Ken Cadwell and 5 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
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  4. Review
  5. Review
  6. Journal of clinical medicine · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Juan GagoVilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, New York, USA.
Thomas D FilardoDivision of Infectious Diseases and Immunology, Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA.
Sarah ConderinoDivision of Epidemiology, Department of Population Health, New York University Grossman School of Medicine, New York, New York, USA.
Samuel J MagazinerDivision of Infectious Diseases and Immunology, Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA.
Yanina DubrovskayaDivision of Infectious Diseases and Immunology, Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA.
Kenneth InglimaDepartment of Pathology, New York University Grossman School of Medicine, New York, New York, USA.
Eduardo IturrateDepartment of Medicine, New York University Grossman School of Medicine, New York, New York, USA.
Alejandro PirontiDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Jonas SchluterDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Ken CadwellDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Sarah HochmanDivision of Infectious Diseases and Immunology, Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA.
Huilin LiDivision of Biostatistics, Department of Population Health, New York University Grossman School of Medicine, New York, New York, USA.ORCID https://orcid.org/0000-0002-8288-7068
Victor J TorresDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Lorna E ThorpeDivision of Epidemiology, Department of Population Health, New York University Grossman School of Medicine, New York, New York, USA.
Bo ShopsinDivision of Infectious Diseases and Immunology, Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA.
New York University · USNYU Langone Health · USTisch Hospital · US

Funding

Mechanisms of MRSA intestinal colonizationR01AI140754 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO · 2020 to 2024
$3.5M
Host-pathogen interactions during hospital adaptation of MRSAR01AI137336 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO, YANAI, ITAI · 2019 to 2022
$3.3M
The unleashed microbiome of cancer patients as a discovery platform for rational microbiome engineeringDP2AI164318 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SCHLUTER, JONAS · 2021 to 2025
$2.5M
Investigating the relationship between antibiotics and nosocomial pneumonia.R21AI149350 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TORRES, VICTOR J. · 2020 to 2021
$466k
ACL HHS U01CK000590NCCDPHP CDC HHS U48 DP006396NIAID NIH HHS DP2 AI164318NIAID NIH HHS R01 AI137336NIAID NIH HHS R01 AI140754NIAID NIH HHS R21 AI149350
6 · The paper itself

Abstract

Background: The epidemiology of nosocomial bloodstream infections (NBSIs) in patients with coronavirus disease 2019 (COVID-19) is poorly understood, due in part to substantial disease heterogeneity resulting from multiple potential pathogens. Methods: We identified risk factors for NBSIs and examined the association between NBSIs and mortality in a retrospective cohort of patients hospitalized with COVID-19 in 2 New York City hospitals during the height of the pandemic. We adjusted for the potential effects of factors likely to confound that association, including age, race, illness severity upon admission, and underlying health status. Results: Between January 1 and October 1, 2020, 1403 patients had a positive blood culture, and 79 and 101 met the stringent criteria for NBSI among non-COVID-19 and COVID-19 patients, respectively. NBSIs occurred almost exclusively among patients who were severely ill with COVID-19 at hospital admission. NBSIs were associated with elevated mortality, even after adjusting for baseline differences in COVID-19 illness (55% cases vs 45% controls; Conclusions: Pathogen species and mortality exhibited temporal differences. Early recognition of risk factors among COVID-19 patients could potentially decrease NBSI-associated mortality through early COVID-19 and antimicrobial treatment.

Indexed as

19bloodstream infectionCoV2COVIDnosocomialSARS

Identifiers

PMID35607701
PMCPMC8992347
OpenAlexW4225875717

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.