Evidence map›Paper›PMID 35607599›Full record

ArticleJournal of asthma and allergy2022

Staph's Toxins IgE Antibodies and Its Relation to the Severity of Allergic Rhinitis.

Rosa Ivett Guzmán-Avilán, Sandra Nora González-Díaz, Katia Denisse Guzmán-Avilán, Carlos De la Cruz-De la Cruz, Humberto de León-Gutiérrez, Santos Guzmán-López

Open access · goldAbstract read
In one paragraph

Article in Journal of asthma and allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rosa Ivett Guzmán-Avilán *Centro Regional de Alergia e Inmunología Clínica (CRAIC), Hospital Universitario "Dr. José E. González", Universidad Autónoma de Nuevo León, Monterrey, 64460, Nuevo León, México.
Sandra Nora González-Díaz *Centro Regional de Alergia e Inmunología Clínica (CRAIC), Hospital Universitario "Dr. José E. González", Universidad Autónoma de Nuevo León, Monterrey, 64460, Nuevo León, México.ORCID 0000-0002-3612-0042
Katia Denisse Guzmán-AvilánCentro Regional de Alergia e Inmunología Clínica (CRAIC), Hospital Universitario "Dr. José E. González", Universidad Autónoma de Nuevo León, Monterrey, 64460, Nuevo León, México.
Carlos De la Cruz-De la CruzEscuela de medicina y Hospital Universitario "Dr. José E. González", Universidad Autónoma de Nuevo León, Monterrey, 64460, Nuevo León, México.ORCID 0000-0002-6091-6374
Humberto de León-GutiérrezDepartamento de Anatomía Humana, Facultad de Medicina y Hospital Universitario "Dr. José E. González", Universidad Autónoma de Nuevo León, Monterrey, 64460, Nuevo León, México.
Santos Guzmán-LópezDepartamento de Anatomía Humana, Facultad de Medicina y Hospital Universitario "Dr. José E. González", Universidad Autónoma de Nuevo León, Monterrey, 64460, Nuevo León, México.ORCID 0000-0003-4100-1360
Universidad Autónoma de Nuevo León · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Specific IgE against Methods: A cross-sectional, comparative non-blinded survey was made at the Regional Center for Allergy and Clinical Immunology. Ninety-nine adults between 18 and 70 years of age with allergic rhinitis (AR) and without allergic rhinitis (wAR) were recruited. A clinical history and demographic data, and allergic sensitization patterns to 35 aeroallergens were obtained, and participants were classified according to their severity using the Allergic Rhinitis and Its Impact on Asthma (ARIA) classification. Specific IgE levels were determined using ImmunoCAP™ 100 platform. Results: The median age (IQR) of the participants was 23 (20-33.7); 56.2% were women. The most frequent comorbidities were asthma and obesity. Of the patients with AR, 46.7% were classified as mild intermittent and 25% as moderate persistent. IgE levels against staph toxins A, B, and TSST were significantly higher in the AR group vs the wAR group [median IQR 0.01 (0.01-0.03) vs. 0.01 (0-0.02), p = 0.01; 0.02 (0.01-0.03) vs. 0.01 (0-0.02), p= 0.02; 0.04 (0.02-0.09) vs. 0.01 (0-0.04), p=0.002, respectably]. A significant difference was found in serum IgE levels against Staph B toxin between severity subgroups. Conclusion: People with AR have higher IgE levels against staph toxins A, B and TSST than wAR subjects. However, it is not possible declare that the IgE titers were related to disease severity.

Indexed as

allergic rhinitisARIAIgEstaphylococcal superantigensStaphylococcus aureus

Identifiers

PMID35607599
PMCPMC9123909
OpenAlexW4280653342

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.