Evidence map›Paper›PMID 35607563›Full record

ArticleCureus2022

Bilateral Adrenalectomy in a Patient With Refractory Primary Aldosteronism Due to Adrenal Hyperplasia.

Luis Marín-Martínez, Antonio J Ríos-Vergara, Georgios Kyriakos, Maria C Álvarez-Martín, Enrique Hernández-Alonso

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Luis Marín-MartínezEndocrinology and Nutrition, Hospital General Universitario Santa Lucía, Cartagena, ESP.
Antonio J Ríos-VergaraEndocrinology and Nutrition, Hospital General Universitario Santa Lucía, Cartagena, ESP.
Georgios KyriakosEndocrinology and Nutrition, Hospital General Universitario Santa Lucía, Cartagena, ESP.
Maria C Álvarez-MartínEndocrinology and Nutrition, Hospital General Universitario Santa Lucía, Cartagena, ESP.
Enrique Hernández-AlonsoEndocrinology and Nutrition, Hospital General Universitario Santa Lucía, Cartagena, ESP.
Santa Lucía University General Hospital · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary aldosteronism (PA) is a frequent cause of secondary hypertension. The main cause of PA is bilateral adrenal hyperplasia, and treatment is usually medical with mineralocorticoid receptor antagonists (MRAs) such as spironolactone or eplerenone. In this paper, we present a rare clinical case of a middle-aged female with refractory arterial hypertension and hypokalemia that complementary medical tests confirmed PA due to bilateral hyperplasia, and despite a maximum dose of spironolactone and oral potassium supplements, there was no clinical response. Because of this, finally, the patient needed surgical treatment based on bilateral adrenalectomy, which was effective. This is unusual and poorly described in the medical literature.

Indexed as

adrenal hyperplasiabilateral adrenalectomyhypokalemiaprimary aldosteronismresistant hypertension

Identifiers

PMID35607563
PMCPMC9123349
OpenAlexW4224212438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.