ArticleNeural plasticity2022
Brain Network Changes in Lumbar Disc Herniation Induced Chronic Nerve Roots Compression Syndromes.
Article in Neural plasticity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Brain network properties in chronic pain-a systematic review and meta-analysis of graph-based connectivity metrics.Frontiers in neuroscience · 2025Pooled it
- Trial
- Central and peripheral factors moderating pain effects on motor control and disability in chronic lumbosacral radicular pain.Journal of neuroengineering and rehabilitation · 2025Article
- Electroacupuncture for the Subacute Stage of Lumbar Disc Herniation: A Randomized Controlled Trial Protocol with EEG.Journal of pain research · 2025Article
- Graph Metrics Reveal Brain Network Topological Property in Neuropathic Pain Patients: A Systematic Review.Journal of pain research · 2024Review
- Traditional Chinese Manual Therapy (Tuina) reshape the function of default mode network in patients with lumbar disc herniation.Frontiers in neuroscience · 2023Article
- Unraveling the PVNMolecular painArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lumbar disc herniation (LDH) induced nerve compression syndromes have been a prevalent problem with complex neural mechanisms. Changes in distributed brain areas are involved in the occurrence and persistence of syndromes. The present study aimed to investigate the changes of brain functional network in LDH patients with chronic sciatica using graph theory analysis. A total of thirty LDH adults presenting L4 and/or L5 root (s) compression syndromes (LDH group) and thirty age-, sex-, BMI- and education-matched healthy control (HC group) were recruited for functional MRI scan. Whole-brain functional network was constructed for each participant using Pearson's correlation. Global and nodal properties were calculated and compared between two groups, including small-worldness index, clustering coefficient, characteristic path length, degree centrality (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.