Evidence map›Paper›PMID 35606826›Full record

ArticleTrials2022

The use of transcranial direct current stimulation (tDCS) to reduce impulsivity and aggression in adults with mild intellectual developmental disabilities: the tDCS-RIADD randomised controlled trial protocol.

Najat Khalifa, Emily R Hawken, Andrew Bickle, Mariel Cabrera, Travis Heath, Andrew Drury, Jessica Jones, Muhammad Ayub

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Najat KhalifaDepartment of Psychiatry, Queen's University, Kingston, Ontario, Canada. nrk2@queensu.ca.ORCID http://orcid.org/0000-0002-2690-9736
Emily R HawkenDepartment of Psychiatry, Queen's University, Kingston, Ontario, Canada.
Andrew BickleDepartment of Psychiatry, Queen's University, Kingston, Ontario, Canada.
Mariel CabreraDepartment of Psychiatry, Queen's University, Kingston, Ontario, Canada.
Travis HeathProvidence Care Hospital, Kingston, Ontario, Canada.
Andrew DruryDepartment of Psychiatry, Queen's University, Kingston, Ontario, Canada.
Jessica JonesDepartment of Psychiatry, Queen's University, Kingston, Ontario, Canada.
Muhammad AyubDepartment of Psychiatry, Queen's University, Kingston, Ontario, Canada.
Queen's University · CAProvidence Health Care · CA

Funding

faculty of health sciences, queen's university TRAQ DSS 6029484
6 · The paper itself

Abstract

backgroundChallenging behaviours, in particular aggressive behaviours, are prevalent among people with intellectual developmental disabilities. Predictors of challenging behaviours are numerous, including past history of aggression, poor coping skills and impulsivity. Factors like motor or rapid-response impulsivity (RRI) have neurobiological underpinnings that may be amenable to change via neuromodulation using non-invasive brain stimulation techniques like transcranial direct current stimulation (tDCS).

methodsThis study aims to determine the efficacy of anodal tDCS in reducing RRI and incidents of aggression in people with intellectual developmental disabilities (IDD) in residential or hospital settings. Using a single blind, randomised, sham-controlled trial design, adults with IDD, with a history of impulsivity leading to aggression, will be randomised to receive either repetitive anodal or sham tDCS applied to the left dorsolateral prefrontal cortex. Outcome measures assessing impulsivity and aggression will be collected for up to 1 month following the last tDCS session. DISCUSSION: The results of this study may pave the way for developing targeted interventions for impulsivity and aggressive behaviours in people with IDD.

Indexed as

Transcranial Direct Current StimulationAdultAggressionChildDevelopmental DisabilitiesDouble-Blind MethodHumansImpulsive BehaviorPrefrontal CortexRandomized Controlled Trials as TopicSingle-Blind MethodAggressionDevelopmental disabilityImpulsivityNeurostimulationtDCS

Identifiers

PMID35606826
PMCPMC9125841
OpenAlexW4281398040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.