Evidence map›Paper›PMID 35606744›Full record

ArticleBMC pediatrics2022

Inter-centre comparison of data on surgery and speech outcomes at 5 years of age based on the Swedish quality registry for patients born with cleft palate with or without cleft lip.

Kristina Klintö, Marie Eriksson, Avni Abdiu, Karin Brunnegård, Jenny Cajander, Emilie Hagberg, Malin Hakelius, Christina Havstam, Hans Mark, Åsa Okhiria and 3 more

Abstract read
In one paragraph

Article in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Longitudinal Speech Outcomes in Foreign-Born and Native-Born Children in Sweden with Cleft Palate, and Influence of Palatal Surgery Timing.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  2. Speech Outcomes in 5-Year-Olds Born With Cleft Palate With and Without Robin Sequence-A Swedish Registry Study.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  3. Examining Percent Consonants Correct Produced by Preschool Children With and Without Cleft Palate Using the American English Phrase Sample.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  4. Article
  5. How Cleft Type and Width Affect the Rate of Secondary Palatal Surgery and Articulation Proficiency in 5-Year-Olds With Cleft Palate.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  6. Velopharyngeal Competence in Children With Cleft Palate: Related Factors and Longitudinal Development.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  7. Article
  8. Exploring the Needs of Young People Born With Cleft Lip and/or Palate Approaching End of Routine Care, in the UK.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  9. Examining Factors That Impact Speech Acceptability and Intelligibility in 4- to 7-Year-Old Children With Cleft Palate.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  10. Reliability of Variables of Consonant Production and Velopharyngeal Competence in 10-year-olds with Cleft Palate Using Multiple Raters.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kristina KlintöDepartment of Clinical Sciences in Malmö, Lund University, Malmö, Sweden. kristina.klinto@med.lu.se.ORCID 0000-0002-7044-9386
Marie ErikssonDepartment of Statistics, USBE, Umeå University, Umeå, Sweden.
Avni AbdiuDepartment of Hand Surgery, Plastic Surgery and Burns and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Karin BrunnegårdDepartment of Clinical Sciences, Speech and Language Pathology, Umeå University, Umeå, Sweden.
Jenny CajanderDepartment for Surgical and Perioperative Sciences, Umeå University, Umeå, Sweden.
Emilie HagbergMedical Unit Speech and Language Pathology and Department of Plastic Surgery and Craniofacial Surgery, Karolinska University Hospital, Stockholm, Sweden.
Malin HakeliusDepartment of Plastic and Maxillofacial Surgery, Uppsala University Hospital, Uppsala, Sweden.
Christina HavstamDepartment of Otorhinolaryngology, Division of Speech and Language Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Hans MarkDepartment of Plastic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden.
Åsa OkhiriaDepartment of Speech-Language Pathology, Uppsala University Hospital, Uppsala, Sweden.
Petra PetersonDepartment of Plastic Surgery and Craniofacial Surgery, Karolinska University Hospital, Stockholm, Sweden.
Kristina SvenssonSpeech and Language Therapy Unit, Linköping University Hospital, Linköping, Sweden.
Magnus BeckerDepartment of Clinical Sciences in Malmö, Lund University, Malmö, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of the Swedish cleft lip and palate registry (CLP registry) is to promote quality control, research and improvement of treatment, by the comparison of long-term results. The aim was to compare data from the CLP registry among the six treatment centres, regarding data on surgery and speech outcomes at 5 years of age.

methodsThe participants were 430 children born in Sweden from 2009 to 2014, with cleft palate with or without cleft lip and without known syndromes and/or additional malformations. The number of primary and secondary palatal surgeries up to 5 years of age, timing of the last primary palatal surgery, percentage consonants correct, percentage non-oral speech errors and perceived velopharyngeal competence at 5 years were assessed. Multivariable binary logistic regression adjusted for sex and cleft type was used to compare results between the six centres.

resultsAt one centre (centre 4), the palate was closed in one to three stages, and at the remaining centres in one or two stages. At centre 4, more children underwent a higher number of palatal surgeries, and the last primary palatal surgery was performed at a higher age. Children in centre 4 were also less likely to achieve ≥86% correct consonants (OR = 0.169, P = < 0.001), have no non-oral speech errors (OR = 0.347, P = < 0.001), or have competent or marginally incompetent velopharyngeal competence (OR = 0.244, P = < 0.001), compared to the average results of the other centres. No clear association between patient volume and speech outcome was observed.

conclusionsThe results indicated the risk of a negative speech result if the last primary palatal surgery was performed after 25 months of age. Whether the cleft in the palate was closed in one or two stages did not affect speech outcome. The Swedish CLP registry can be used for open comparisons of treatment results to provide the basis for improvements of treatment methods. If deviating negative results are seen consistently at one centre, this information should be acted upon by further investigation and analysis, making changes to the treatment protocol as needed.

Indexed as

Cleft LipCleft PalateChildChild, PreschoolHumansRegistriesSpeechSwedenTreatment OutcomeCleft lip and palateRegistrySpeechSurgery

Identifiers

PMID35606744
PMCPMC9125901

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.