ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2022
Microcirculation-guided treatment improves tissue perfusion and hemodynamic coherence in surgical patients with septic shock.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Haemodynamic effects of selective venoconstriction with centhaquine in spontaneously breathing patients with mixed hypovolaemic-vasodilatory shock.Experimental physiology · 2026Trial
- Anisodamine hydrobromide reduces 28-day mortality in septic shock: a randomized controlled.Frontiers in pharmacology · 2026Trial
- Protease-Activated Receptors (PARs): Biology and Therapeutic Potential in Perioperative Stroke.Translational stroke research · 2025Review
- On the Intensity of the Microvascular Magnetic Field in Normal State and Septic Shock.Journal of clinical medicine · 2025Article
- Characterization of Sublingual Microvascular Tortuosity in Steady-State Physiology and Septic Shock.Biomedicines · 2025Article
- Intestinal oxygen utilisation and cellular adaptation during intestinal ischaemia-reperfusion injury.Clinical and translational medicine · 2025Review
- Transitions from Aerobic to Anaerobic Metabolism and Oxygen Debt during Elective Major and Emergency Non-Cardiac Surgery.Biomedicines · 2024Article
- The association between prolonged capillary refill time and microcirculation changes in children with sepsis.BMC pediatrics · 2024Article
- Albumin as a prognostic marker of 30-day mortality in septic patients admitted to the emergency department.Internal and emergency medicine · 2023Observational
- The Relation of Calculated Plasma Volume Status to Sublingual Microcirculatory Blood Flow and Organ Injury.Journal of personalized medicine · 2023Article
- General Critical Care, Temperature Control, and End-of-Life Decision Making in Patients Resuscitated from Cardiac Arrest.Journal of clinical medicine · 2023Review
- Cutting-Edge Approaches in Respiratory and Critical Care Medicine.Journal of personalized medicine · 2023Article
- Association of vasopressors with mortality in critically ill patients with COVID-19: a systematic review and meta-analysis.Anesthesiology and perioperative science · 2023Review
- Relationship of Effective Circulating Volume with Sublingual Red Blood Cell Velocity and Microvessel Pressure Difference: A Clinical Investigation and Computational Fluid Dynamics Modeling.Journal of clinical medicine · 2022Article
- Current Challenges in the Management of Sepsis and Septic Shock: Personalized, Physiology-Guided Treatment.Journal of clinical medicine · 2022Article
- Association of Preoperative Basal Inflammatory State, Measured by Plasma suPAR Levels, with Intraoperative Sublingual Microvascular Perfusion in Patients Undergoing Major Non-Cardiac Surgery.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSevere sepsis and septic shock may impair microcirculatory perfusion and cause organ dysfunction. The aim of this pilot study was to assess a new microcirculation-guided resuscitation strategy in patients with septic shock undergoing emergency abdominal surgery.
methodsA microcirculation-guided treatment algorithm was developed and applied intraoperatively following restoration of systemic hemodynamics. Sublingual microcirculation was monitored with Sidestream DarkField (SDF +) imaging technique. The primary objective was to investigate the change in De Backer score, Consensus Proportion of Perfused Vessels (Consensus PPV), and Consensus PPV (small) and its association with venous-to-arterial carbon dioxide difference (v-aPCO
resultsThirteen consecutive patients were included in the study. Microcirculation-guided resuscitation resulted in an increase of 0.49 mm
conclusionsThe intraoperative use of microcirculation-guided resuscitation strategy may improve tissue perfusion and hemodynamic coherence in patients with septic shock.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.