Evidence map›Paper›PMID 35606517›Full record

ArticleNature structural & molecular biology2022

Mammalian PERIOD2 regulates H2A.Z incorporation in chromatin to orchestrate circadian negative feedback.

Kevin Tartour, Francesca Andriani, Eric G Folco, Dominika Letkova, Raphael Schneider, Isahak Saidi, Tomoki Sato, Patrick-Simon Welz, Salvador Aznar Benitah, Cédric Allier and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature structural & molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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  7. Circadian geneOpen life sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Kevin Tartour *Institut de Genomique Fonctionnelle de Lyon, Univ Lyon, CNRS UMR 5242, Ecole Normale Superieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Francesca Andriani *Institut de Genomique Fonctionnelle de Lyon, Univ Lyon, CNRS UMR 5242, Ecole Normale Superieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France.ORCID 0000-0002-6178-7789
Eric G FolcoInstitut de Genomique Fonctionnelle de Lyon, Univ Lyon, CNRS UMR 5242, Ecole Normale Superieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Dominika LetkovaInstitut de Genomique Fonctionnelle de Lyon, Univ Lyon, CNRS UMR 5242, Ecole Normale Superieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Raphael SchneiderInstitut de Genomique Fonctionnelle de Lyon, Univ Lyon, CNRS UMR 5242, Ecole Normale Superieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Isahak SaidiInstitut de Genomique Fonctionnelle de Lyon, Univ Lyon, CNRS UMR 5242, Ecole Normale Superieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Tomoki SatoLaboratory of Nutritional Biochemistry, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka, Japan.
Patrick-Simon WelzProgram in Cancer Research, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.ORCID 0000-0001-8370-625X
Salvador Aznar BenitahInstitute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.ORCID 0000-0002-9059-5049
Cédric AllierUniversité Grenoble-Alpes, CEA, LETI, DTBS, Grenoble, France.
Kiran PadmanabhanInstitut de Genomique Fonctionnelle de Lyon, Univ Lyon, CNRS UMR 5242, Ecole Normale Superieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France. kiran.padmanabhan@ens-lyon.fr.ORCID 0000-0001-7020-1682
Université Claude Bernard Lyon 1 · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRInstitució Catalana de Recerca i Estudis Avançats · ESInstitute for Research in Biomedicine · ESUniversity of Shizuoka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mammalian circadian oscillators are built on a feedback loop in which the activity of the transcription factor CLOCK-BMAL1 is repressed by the PER-CRY complex. Here, we show that murine Per

Indexed as

ChromatinHistonesAnimalsARNTL Transcription FactorsCircadian RhythmFeedbackMammalsMiceNucleosomesPeriod Circadian ProteinsARNTL Transcription FactorsChromatinHistonesNucleosomesPer2 protein, mousePeriod Circadian Proteins

Identifiers

PMID35606517
OpenAlexW4281286577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.