ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022
Spontaneous Spiking Is Governed by Broadband Fluctuations.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 30 citations in OpenAlex.
- Cannabidiol blood metabolite levels after cannabidiol treatment are associated with broadband EEG changes and improvements in visuomotor and non-verbal cognitive abilities in boys with autism requiring higher levels of support.Translational psychiatry · 2026Trial
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- Spatiotemporal Divergence Between Intrinsic And Evoked Cortical Activity Predicts Visual Detection.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Sequential visual stimuli increase high frequency power in the visual cortex.Scientific reports · 2026Article
- Cannabidiol blood metabolite levels after cannabidiol treatment are associated with broadband EEG changes and improvements in visuomotor and non-verbal cognitive abilities in boys with autism requiring higher levels of support.medRxiv : the preprint server for health sciences · 2025Article
- Theta-phase locking of single neurons during human spatial memory.Nature communications · 2025Article
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- Horizontal cortical connections shape intrinsic traveling waves into feature-selective motifs that regulate perceptual sensitivity.Cell reports · 2024Article
- Electrophysiological dynamics of salience, default mode, and frontoparietal networks during episodic memory formation and recall: A multi-experiment iEEG replication.bioRxiv : the preprint server for biology · 2024Article
- A high-density multi-electrode platform examining the effects of radiation on in vitro cortical networks.Scientific reports · 2024Article
- Coupled oscillations orchestrate selective information transmission in visual cortex.PNAS nexus · 2024Article
- Horizontal cortical connections shape intrinsic traveling waves into feature-selective motifs that regulate perceptual sensitivity.Research square · 2024Article
- Different Methods to Estimate the Phase of Neural Rhythms Agree But Only During Times of Low Uncertainty.eNeuro · 2023Article
- Review
- Different methods to estimate the phase of neural rhythms agree, but only during times of low uncertainty.bioRxiv : the preprint server for biology · 2023Article
- Article
- Dynamic attention signalling in V4: Relation to fast-spiking/non-fast-spiking cell class and population coupling.The European journal of neuroscience · 2023Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Populations of cortical neurons generate rhythmic fluctuations in their ongoing spontaneous activity. These fluctuations can be seen in the local field potential (LFP), which reflects summed return currents from synaptic activity in the local population near a recording electrode. The LFP is spectrally broad, and many researchers view this breadth as containing many narrowband oscillatory components that may have distinct functional roles. This view is supported by the observation that the phase of narrowband oscillations is often correlated with cortical excitability and can relate to the timing of spiking activity and the fidelity of sensory evoked responses. Accordingly, researchers commonly tune in to these channels by narrowband filtering the LFP. Alternatively, neural activity may be fundamentally broadband and composed of transient, nonstationary rhythms that are difficult to approximate as oscillations. In this view, the instantaneous state of the broad ensemble relates directly to the excitability of the local population with no particular allegiance to any frequency band. To test between these alternatives, we asked whether the spiking activity of neocortical neurons in marmoset of either sex is better aligned with the phase of the LFP within narrow frequency bands or with a broadband measure. We find that the phase of broadband LFP fluctuations provides a better predictor of spike timing than the phase after filtering in narrow bands. These results challenge the view of the neocortex as a system composed of narrowband oscillators and supports a view in which neural activity fluctuations are intrinsically broadband.
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