Evidence map›Paper›PMID 35605949›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2022

Cholera outbreaks in sub-Saharan Africa during 2010-2019: a descriptive analysis.

Qulu Zheng, Francisco J Luquero, Iza Ciglenecki, Joseph F Wamala, Abdinasir Abubakar, Placide Welo, Mukemil Hussen, Mesfin Wossen, Sebastian Yennan, Alama Keita and 3 more

Abstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Qulu ZhengDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Francisco J LuqueroDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Global Alliance for Vaccines and Immunization (GAVI), Geneva, Switzerland.
Iza CigleneckiMédecins Sans Frontières, Geneva, Switzerland.
Joseph F WamalaWorld Health Organization, Juba, South Sudan.
Abdinasir AbubakarWHO, Regional Office for Eastern Mediterranean, Cairo, Egypt.
Placide WeloPNECHOL-MD, Community IMCI, Ministry of Health, Democratic Republic of the Congo.
Mukemil HussenDisease and Health Events Surveillance and Response Directorate, Ethiopia Public Health Institute, Addis Ababa, Ethiopia.
Mesfin WossenDisease and Health Events Surveillance and Response Directorate, Ethiopia Public Health Institute, Addis Ababa, Ethiopia.
Sebastian YennanSurveillance and Epidemiology, Nigeria Centre for Disease Control, Abuja, Nigeria.
Alama KeitaRegional Office for West & Central Africa, UNICEF, Dakar, Senegal.
Justin LesslerDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Andrew S AzmanDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Elizabeth C LeeDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundCholera remains a public health threat but is inequitably distributed across sub-Saharan Africa. Lack of standardized reporting and inconsistent outbreak definitions limit our understanding of cholera outbreak epidemiology.

methodsFrom a database of cholera incidence and mortality, we extracted data from sub-Saharan Africa and reconstructed outbreaks of suspected cholera starting in January 2010 to December 2019 based on location-specific average weekly incidence rate thresholds. We then described the distribution of key outbreak metrics.

resultsWe identified 999 suspected cholera outbreaks in 744 regions across 25 sub-Saharan African countries. The outbreak periods accounted for 1.8 billion person-months (2% of the total during this period) from January 2010 to January 2020. Among 692 outbreaks reported from second-level administrative units (e.g., districts), the median attack rate was 0.8 per 1000 people (interquartile range (IQR), 0.3-2.4 per 1000), the median epidemic duration was 13 weeks (IQR, 8-19), and the median early outbreak reproductive number was 1.8 (range, 1.1-3.5). Larger attack rates were associated with longer times to outbreak peak, longer epidemic durations, and lower case fatality risks.

conclusionsThis study provides a baseline from which the progress toward cholera control and essential statistics to inform outbreak management in sub-Saharan Africa can be monitored.

Indexed as

CholeraAfrica South of the SaharaDisease OutbreaksHumansIncidencePublic HealthCholeraOutbreaksSub-Saharan Africa

Identifiers

PMID35605949
PMCPMC9439956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.