Evidence map›Paper›PMID 35605768›Full record

ArticleAnnals of epidemiology2022

Job loss and fetal growth restriction: identification of critical trimesters of exposure.

Samantha Gailey, Laust H Mortensen, Tim A Bruckner

Open access · greenAbstract read
In one paragraph

Article in Annals of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Samantha GaileyMinnesota Population Center, University of Minnesota, Twin Cities, Minnesota, USA. Electronic address: gaile009@umn.edu.
Laust H MortensenStatistics Denmark, Copenhagen, Denmark; Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Tim A BrucknerUniversity of California Irvine, Center for Population, Inequality and Policy and Program in Public Health, Irvine, California, USA.
University of California, Irvine · USUniversity of Copenhagen · DKUniversity of Minnesota · US

Funding

Minnesota Population Center Science and Technical CoreP2CHD041023 · NICHD · UNIVERSITY OF MINNESOTA · PI THERESA LOUISE OSYPUK · 2016 to 2026
$4.3M
Spatial Analysis CoreR24HD041023 · NICHD · UNIVERSITY OF MINNESOTA TWIN CITIES · PI RUGGLES, STEVE · 2001 to 2016
$4.1M
Interdisciplinary Population Health Science Training: Linking Multilevel Forces Across TimeT32HD095134 · NICHD · UNIVERSITY OF MINNESOTA · PI THERESA LOUISE OSYPUK, John Robert Warren · 2019 to 2026
$2.5M
NICHD NIH HHS P2C HD041023NICHD NIH HHS R24 HD041023NICHD NIH HHS T32 HD095134
6 · The paper itself

Abstract

purposePrevious research suggests that job loss in a household during pregnancy may perturb fetal growth. However, this work often cannot rule out unmeasured confounding due to selection into job loss. Recent work using data on exogenous job loss (due to a plant closure) finds that a father's unexpected job loss during his spouse's pregnancy increases the risk of a low weight birth. Using a unique set of linked registries in Denmark, we build on this work and examine whether associations between a father's unexpected job loss and low birthweight differ by trimester of in utero exposure. We additionally examine trimester-specific associations of job loss with small-for-gestational-age, a proxy for restricted fetal growth, which may cause low birthweight.

methodsWe apply a sibling control design to over 1.4 million live births in Denmark, 1980 to 2017, to examine whether this plausibly exogenous form of job loss corresponds with increased risk of low weight or small-for-gestational-age births, depending on the timing of displacement in the first, second, or third trimester.

resultsResults indicate an elevated risk of low birthweight (OR = 1.80, 95% CI: 1.24, 2.62) and small-for-gestational-age (OR = 1.40, 95% CI: 1.02, 1.93) among gestations exposed to job loss in the second trimester of pregnancy. Sensitivity analyses using continuous outcome measures (e.g., birthweight in grams, birthweight for gestational age percentile) and maternal fixed effects analyses produce substantively similar inference.

conclusionsFindings support the notion that unexpected job loss may affect fetal growth and that the second trimester in particular appears sensitive to this external stressor.

Indexed as

Fetal Growth RetardationInfant, Small for Gestational AgeBirth WeightFemaleFetal DevelopmentGestational AgeHumansInfant, NewbornPregnancyPregnancy TrimestersBirth outcomesFetal growthJob lossSibling comparison designsUnemployment

Identifiers

PMID35605768
PMCPMC10194830
OpenAlexW4281264428

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.