Evidence map›Paper›PMID 35605214›Full record

ArticleBrazilian journal of cardiovascular surgery2022

Pediatric Heart Transplant: Initial Experience in a Tertiary Center in Brazil.

Francisco Candido Monteiro Cajueiro, Ulisses Alexandre Croti, Alexandra Regina Siscar Barufi, André Luís de Andrade Bodini, Karolyne Barroca Sanches Postigo, Carlos Henrique De Marchi, Fernando Cesar Gimenes Barbosa Santos, Lilian Beani, Bruna Cury Borim, Moacir Fernandes Godoy and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Brazilian journal of cardiovascular surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Francisco Candido Monteiro CajueiroPediatric Cardiology and Cardiovascular Surgery, CardioPedBrasil - Hospital da Criança e Maternidade de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil.
Ulisses Alexandre CrotiPediatric Cardiology and Cardiovascular Surgery, CardioPedBrasil - Hospital da Criança e Maternidade de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil.ORCID 0000-0002-1127-4782
Alexandra Regina Siscar BarufiPediatric Cardiology and Cardiovascular Surgery, CardioPedBrasil - Hospital da Criança e Maternidade de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil.
André Luís de Andrade BodiniPediatric Cardiology and Cardiovascular Surgery, CardioPedBrasil - Hospital da Criança e Maternidade de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil.
Karolyne Barroca Sanches PostigoPediatric Cardiology and Cardiovascular Surgery, CardioPedBrasil - Hospital da Criança e Maternidade de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil.
Carlos Henrique De MarchiPediatric Cardiology and Cardiovascular Surgery, CardioPedBrasil - Hospital da Criança e Maternidade de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil.
Fernando Cesar Gimenes Barbosa SantosPediatric Cardiology and Cardiovascular Surgery, CardioPedBrasil - Hospital da Criança e Maternidade de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil.
Lilian BeaniPediatric Cardiology and Cardiovascular Surgery, CardioPedBrasil - Hospital da Criança e Maternidade de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil.
Bruna Cury BorimPediatric Cardiology and Cardiovascular Surgery, CardioPedBrasil - Hospital da Criança e Maternidade de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil.
Moacir Fernandes GodoyPediatric Cardiology and Cardiovascular Surgery, CardioPedBrasil - Hospital da Criança e Maternidade de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil.
Airton Camacho MoscardiniPediatric Cardiology and Cardiovascular Surgery, CardioPedBrasil - Hospital da Criança e Maternidade de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil.
Faculdade de Medicina de São José do Rio Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPediatric heart transplantation is the definitive therapy for children with end-stage heart failure. This paper describes our initial experience in pediatric heart transplantation in a tertiary center in Brazil.

methodsThis is a historical prospective descriptive cohort study based on a review of the medical records of children undergoing heart transplantation at Hospital de Base and Hospital da Criança e Maternidade de São José do Rio Preto. Variables were displayed as frequency, mean, or median. Statistical analysis and Kaplan-Meier actuarial curve were obtained with the aid of Microsoft® Excel® 2019 and STATSDirect version 3.3.5.

resultsBetween January 2010 and December 2020, ten children underwent bicaval orthotopic heart transplantation, 30% of which were under one year of age. Nine patients had end-stage heart failure (International Society for Heart and Lung Transplantation-Heart Failure D) and 50% of the recipients were transplanted under conditions of progressive clinical deterioration (Interagency Registry for Mechanically Assisted Circulatory Support ≤ 2). Forty percent of the recipients had a panel-reactive antibody > 20% on virtual crossmatch. In the postoperative period, 80% of patients required high dose of inotropic support (vasoactive-inotropic score > 10) for > 48 hours. The death-free survival rate at 131 months was 77.1±14.4%. Most patients (88.9%) in late follow-up had an episode of active cytomegalovirus infection. Cellular rejection, with or without clinical repercussion, was present in 44.4% of the patients.

conclusionPediatric heart transplantation produces acceptable and feasible outcomes as definitive therapy for children with end-stage heart failure.

Indexed as

Heart FailureHeart TransplantationBrazilChildCohort StudiesHumansProspective StudiesRetrospective StudiesTreatment OutcomeCardiologyHeart FailureHeart TransplantationPediatricTreatment Outcome

Identifiers

PMID35605214
PMCPMC9162413
OpenAlexW4282918764

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.