Evidence map›Paper›PMID 35604744›Full record

Trial reportJournal of consulting and clinical psychology2022

The effect of stimulant medication on the learning of academic curricula in children with ADHD: A randomized crossover study.

William E Pelham, Amy R Altszuler, Brittany M Merrill, Joseph S Raiker, Fiona L Macphee, Marcela Ramos, Elizabeth M Gnagy, Andrew R Greiner, Erika K Coles, Carol M Connor and 7 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

William E PelhamDepartment of Psychiatry.ORCID 0000-0003-1480-570X
Amy R AltszulerCenter for Children and Families.
Brittany M MerrillDepartment of Psychology.ORCID 0000-0003-3844-8399
Joseph S RaikerDepartment of Psychology.ORCID 0000-0001-5364-3825
Fiona L MacpheeDepartment of Psychology.
Marcela RamosDepartment of Psychology.ORCID 0000-0002-6379-4552
Elizabeth M GnagyCenter for Children and Families.
Andrew R GreinerCenter for Children and Families.
Erika K ColesDepartment of Psychology.
Carol M ConnorSchool of Education.
Christopher J LoniganDepartment of Psychology.
Lisa BurgerCenter for Children and Families.
Anne S MorrowDepartment of Psychology.ORCID 0000-0001-6340-4801
Xin ZhaoDepartment of Psychology.
James M SwansonDepartment of Pediatrics.
James G WaxmonskyDepartment of Psychiatry.
William E PelhamDepartment of Psychology.ORCID 0000-0002-3195-4478

Funding

Examining Tolerance to CNS Stimulants in ADDR01MH099030 · NIMH · FLORIDA INTERNATIONAL UNIVERSITY · PI PELHAM, WILLIAM E, SWANSON, JAMES M · 2013 to 2017
$3.3M
A Novel Approach to Stimulant-Induced Weight Suppression and its Impact on GrowthR01MH083692 · NIMH · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI PELHAM, WILLIAM E, WAXMONSKY, JAMES GAIER · 2009 to 2014
$3.1M
Family processes underlying adolescent substance use and conduct problems: disentangling correlation and causationK08DA055935 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI William Ellerbe Pelham III · 2022 to 2026
$959k
The impact of the COVID-19 pandemic on adolescent drinking in a longitudinal cohort spanning 21 U.S. citiesR21AA030197 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PELHAM III, WILLIAM ELLERBE · 2022 to 2023
$447k
Identifying Children and Teens at Risk for Early Onset Alcohol Use: An Innovative Application of Machine Learning Algorithms to PreventionF31AA026768 · NIAAA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI PELHAM III, WILLIAM ELLERBE · 2018 to 2019
$88k
NIAAA NIH HHS F31 AA026768NIAAA NIH HHS R21 AA030197NIDA NIH HHS K08 DA055935NIMH NIH HHS R01 MH083692NIMH NIH HHS R01 MH099030
6 · The paper itself

Abstract

objectiveEvaluate whether stimulant medication improves acquisition of academic material in children with attention deficit hyperactivity disorder (ADHD) receiving small-group, content-area instruction in a classroom setting.

methodParticipants were 173 children between the ages of 7 and 12 years old (77% male, 86% Hispanic) who met Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for ADHD and were participating in a therapeutic summer camp. The design was a triple-masked, within-subject, AB/BA crossover trial. Children completed two consecutive phases of daily, 25-min instruction in both (a) subject-area content (science, social studies) and (b) vocabulary. Each phase was a standard instructional unit lasting for 3 weeks. Teachers and aides taught the material to small groups in a summer classroom setting. Each child was randomized to be medicated with daily osmotic-release oral system methylphenidate (OROS-MPH) during either the first or second of the instructional phases, receiving placebo during the other.

resultsMedication had large, salutary, statistically significant effects on children's academic seatwork productivity and classroom behavior on every single day of the instructional period. However, there was no detectable effect of medication on learning the material taught during instruction: Children learned the same amount of subject-area and vocabulary content whether they were taking OROS-MPH or placebo during the instructional period.

conclusionsAcute effects of OROS-MPH on daily academic seatwork productivity and classroom behavior did not translate into improved learning of new academic material taught via small-group, evidence-based instruction. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Indexed as

Attention Deficit Disorder with HyperactivityCentral Nervous System StimulantsMethylphenidateChildCross-Over StudiesCurriculumDouble-Blind MethodFemaleHumansMaleTreatment OutcomeCentral Nervous System StimulantsMethylphenidate

Identifiers

PMID35604744
PMCPMC9443328

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.