Evidence map›Paper›PMID 35604633›Full record

ArticlePharmacoEconomics2022

EQ-5D-Y Value Set for Germany.

Simone Kreimeier, David Mott, Kristina Ludwig, Wolfgang Greiner, IMPACT HTA HRQoL Group

Erratum issuedAbstract read
In one paragraph

Article in PharmacoEconomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Do EQ-5D-Y-3L value sets have common properties, and how do they compare to EQ-5D-5L value sets?The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
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  9. Value set of EQ-5D-Y-3L for Hong Kong.Health and quality of life outcomes · 2026
    Article
  10. An Australian Value Set for the EQ-5D-Y-3L.Health and quality of life outcomes · 2025
    Article
  11. Comparison of the early childhood oral health impact scale (ECOHIS-4D) and EuroQol-5D-Y for measuring oral health-related quality of life utility in children.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Simone KreimeierDepartment of Health Economics and Health Care Management, School of Public Health, Bielefeld University, Bielefeld, Germany. simone.kreimeier@uni-bielefeld.de.ORCID 0000-0002-4832-7833
David MottOffice of Health Economics, London, UK.ORCID 0000-0001-5959-8447
Kristina LudwigDepartment of Health Economics and Health Care Management, School of Public Health, Bielefeld University, Bielefeld, Germany.ORCID 0000-0002-4306-4667
Wolfgang GreinerDepartment of Health Economics and Health Care Management, School of Public Health, Bielefeld University, Bielefeld, Germany.ORCID 0000-0001-9552-6969
IMPACT HTA HRQoL Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDemand is increasing for youth-specific preference-based health-related quality-of-life measures for inclusion in evaluations of healthcare interventions for children and adolescents. The EQ-5D-Youth (EQ-5D-Y) has the potential to become such a preference-based measure.

objectiveThis study applied the recently published EQ-5D-Y valuation protocol to develop a German EQ-5D-Y value set and explored the differences between values given to youth health by parents and non-parents.

methodsTo elicit EQ-5D-Y health state preferences, a representative sample of 1030 adults of the general population completed a discrete choice experiment (DCE) online survey, and 215 adults participated in face-to-face interviews applying composite time trade-off (cTTO). Respondents were asked to consider a 10-year-old child living in the health states. DCE data were modelled using a mixed logit model. To derive the value set, DCE latent scale values were anchored onto adjusted mean cTTO values using a linear mapping approach.

resultsAdult respondents considered pain/discomfort and feeling worried/sad/unhappy as the two most important dimensions in terms of youth health. Adjusted mean cTTO values ranged from - 0.350 for health state 33333 to 0.970 for health state 21111. The EQ-5D-Y value set showed a logical order for all parameter estimates, and predicted values ranged from - 0.283 to 1. Differences in preferences by parental status were mainly observed for cTTO results, where mean values were larger for parents than for non-parents.

conclusionsApplying the valuation protocol, a German EQ-5D-Y value set with internally consistent coefficients was developed. This enables the instrument to be used in economic evaluations of paediatric healthcare interventions.

Indexed as

Health StatusQuality of LifeAdolescentAdultChildCost-Benefit AnalysisGermanyHumansSurveys and Questionnaires

Identifiers

PMID35604633
PMCPMC9124748

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.