Evidence map›Paper›PMID 35604546›Full record

ReviewEpilepsia2023

Seizure forecasting: Bifurcations in the long and winding road.

Maxime O Baud, Timothée Proix, Nicholas M Gregg, Benjamin H Brinkmann, Ewan S Nurse, Mark J Cook, Philippa J Karoly

Abstract readReview
In one paragraph

Review in Epilepsia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Seizure Detection Devices.Journal of clinical medicine · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maxime O BaudSleep-Wake-Epilepsy Center, Center for Experimental Neurology, NeuroTec, Department of Neurology, Inselspital Bern, University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0002-8297-7696
Timothée ProixDepartment of Basic Neurosciences, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Nicholas M GreggBioelectronics Neurophysiology and Engineering Laboratory, Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-6151-043X
Benjamin H BrinkmannBioelectronics Neurophysiology and Engineering Laboratory, Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-2392-8608
Ewan S NurseGraeme Clark Institute, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0001-8981-0074
Mark J CookGraeme Clark Institute, University of Melbourne, Melbourne, Victoria, Australia.
Philippa J KarolyGraeme Clark Institute, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-9879-5854

Funding

Optimizing Pharmacotherapy with Noninvasive Wearable Sensors and Subscalp EEGUG3NS123066 · NINDS · MAYO CLINIC ROCHESTER · PI BRINKMANN, BENJAMIN H, WORRELL, GREGORY A · 2022 to 2024
$1.2M
NINDS NIH HHS UG3 NS123066
6 · The paper itself

Abstract

To date, the unpredictability of seizures remains a source of suffering for people with epilepsy, motivating decades of research into methods to forecast seizures. Originally, only few scientists and neurologists ventured into this niche endeavor, which, given the difficulty of the task, soon turned into a long and winding road. Over the past decade, however, our narrow field has seen a major acceleration, with trials of chronic electroencephalographic devices and the subsequent discovery of cyclical patterns in the occurrence of seizures. Now, a burgeoning science of seizure timing is emerging, which in turn informs best forecasting strategies for upcoming clinical trials. Although the finish line might be in view, many challenges remain to make seizure forecasting a reality. This review covers the most recent scientific, technical, and medical developments, discusses methodology in detail, and sets a number of goals for future studies.

Indexed as

EpilepsySeizuresElectroencephalographyForecastingHumanschronic EEGcircadianmultidienseizure cyclesseizure forecastingwearable devices

Identifiers

PMID35604546
PMCPMC9681938

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.