Evidence map›Paper›PMID 35604341›Full record

ArticleEnvironmental health perspectives2022

Lung Cancer and Radon: Pooled Analysis of Uranium Miners Hired in 1960 or Later.

David B Richardson, Estelle Rage, Paul A Demers, Minh T Do, Nora Fenske, Veronika Deffner, Michaela Kreuzer, Jonathan Samet, Stephen J Bertke, Kaitlin Kelly-Reif and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Lung Cancer Screening and Prevention: Beyond Conventional Strategies in a Rapidly Changing Global Milieu.American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Advances in the Basic Sciences in Thoracic Oncology in the Last 20 Years and Their Translational Impact.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Review
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  16. State-of-the-Art Review on Removal of Naturally Occurring Radioactive Materials in Water.International journal of environmental research and public health · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 5 countries.

David B RichardsonUniversity of California, Irvine, Irvine, California, USA.ORCID 0000-0001-8550-0212
Estelle RageInstitute for Radiological Protection and Nuclear Safety, Fontenay-aux-Roses, France.
Paul A DemersOccupational Cancer Research Centre, Toronto, Canada.
Minh T DoOccupational Cancer Research Centre, Toronto, Canada.
Nora FenskeFederal Office for Radiation Protection, Munich (Neuherberg), Germany.
Veronika DeffnerFederal Office for Radiation Protection, Munich (Neuherberg), Germany.
Michaela KreuzerFederal Office for Radiation Protection, Munich (Neuherberg), Germany.
Jonathan SametColorado School of Public Health, Aurora, Colorado, USA.
Stephen J BertkeNational Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.
Kaitlin Kelly-ReifNational Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.
Mary K Schubauer-BeriganNational Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.
Ladislav TomasekNational Radiation Protection Institute, Prague, Czech Republic.
Lydia B ZablotskaUniversity of California, San Francisco, San Francisco, California, USA.
Charles WigginsUniversity of New Mexico, Albuquerque, New Mexico, USA.
Dominique LaurierInstitute for Radiological Protection and Nuclear Safety, Fontenay-aux-Roses, France.
Federal Office for Radiation Protection · DENational Institute for Occupational Safety and Health · USOccupational Cancer Research Centre · CAColorado School of Public Health · USNational Radiation Protection Institute · CZUniversity of California, Irvine · USUniversity of California, San Francisco · USUniversity of New Mexico · US

Funding

NIOSH CDC HHS R03 OH010946NIOSH CDC HHS R21 OH011452World Health Organization 001
6 · The paper itself

Abstract

backgroundDespite reductions in exposure for workers and the general public, radon remains a leading cause of lung cancer. Prior studies of underground miners depended heavily upon information on deaths among miners employed in the early years of mine operations when exposures were high and tended to be poorly estimated.

objectivesTo strengthen the basis for radiation protection, we report on the follow-up of workers employed in the later periods of mine operations for whom we have more accurate exposure information and for whom exposures tended to be accrued at intensities that are more comparable to contemporary settings.

methodsWe conducted a pooled analysis of cohort studies of lung cancer mortality among 57,873 male uranium miners in Canada, Czech Republic, France, Germany, and the United States, who were first employed in 1960 or later (thereby excluding miners employed during the periods of highest exposure and focusing on miners who tend to have higher quality assessments of radon progeny exposures). We derived estimates of excess relative rate per 100 working level months (ERR/100 WLM) for mortality from lung cancer.

resultsThe analysis included DISCUSSION: Estimates of association between radon progeny exposure and lung cancer mortality among relatively contemporary miners are coherent with estimates used to inform current protection guidelines. https://doi.org/10.1289/EHP10669.

Indexed as

Lung NeoplasmsMinersNeoplasms, Radiation-InducedOccupational DiseasesOccupational ExposureRadonUraniumHumansMaleRadon DaughtersRadonRadon DaughtersUranium

Identifiers

PMID35604341
PMCPMC9126132
OpenAlexW4281385365

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.