Evidence map›Paper›PMID 35604214›Full record

ArticleAntimicrobial agents and chemotherapy2022

Characterization of Glucokinases from Pathogenic Free-Living Amoebae.

Jillian E Milanes, Jimmy Suryadi, Neil P Monaghan, Elijah M Harding, Corbin S Morris, Soren D Rozema, Muhammad M Khalifa, Jennifer E Golden, Isabelle Q Phan, Rachael Zigweid and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Jillian E MilanesEukaryotic Pathogens Innovation Center, Department of Genetics and Biochemistry, Clemson Universitygrid.26090.3d, Clemson, South Carolina, USA.
Jimmy SuryadiEukaryotic Pathogens Innovation Center, Department of Genetics and Biochemistry, Clemson Universitygrid.26090.3d, Clemson, South Carolina, USA.
Neil P MonaghanEukaryotic Pathogens Innovation Center, Department of Genetics and Biochemistry, Clemson Universitygrid.26090.3d, Clemson, South Carolina, USA.
Elijah M HardingEukaryotic Pathogens Innovation Center, Department of Genetics and Biochemistry, Clemson Universitygrid.26090.3d, Clemson, South Carolina, USA.
Corbin S MorrisEukaryotic Pathogens Innovation Center, Department of Genetics and Biochemistry, Clemson Universitygrid.26090.3d, Clemson, South Carolina, USA.
Soren D RozemaSchool of Pharmacy, Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Muhammad M KhalifaSchool of Pharmacy, Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Jennifer E GoldenSchool of Pharmacy, Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-6813-3710
Isabelle Q PhanSeattle Structural Genomics Center for Infectious Disease, Center for Global Infection Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Rachael ZigweidSeattle Structural Genomics Center for Infectious Disease, Center for Global Infection Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Jan AbendrothSeattle Structural Genomics Center for Infectious Disease, Center for Global Infection Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Christopher A RicePharmaceutical and Biomedical Sciences, Center for Drug Discovery, College of Pharmacy, University of Georgiagrid.213876.9, Athens, Georgia, USA.ORCID 0000-0003-0672-9604
Hayden T McCordPharmaceutical and Biomedical Sciences, Center for Drug Discovery, College of Pharmacy, University of Georgiagrid.213876.9, Athens, Georgia, USA.ORCID 0000-0002-6082-7654
Stevin WilsonEukaryotic Pathogens Innovation Center, Department of Genetics and Biochemistry, Clemson Universitygrid.26090.3d, Clemson, South Carolina, USA.
Michael K FenwickSeattle Structural Genomics Center for Infectious Disease, Center for Global Infection Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.ORCID 0000-0001-5066-4962
James C MorrisEukaryotic Pathogens Innovation Center, Department of Genetics and Biochemistry, Clemson Universitygrid.26090.3d, Clemson, South Carolina, USA.ORCID 0000-0003-2515-5714
Clemson University · USUniversity of Wisconsin–Madison · USUniversity of Georgia · US

Funding

Regulation of Cryptosporidium DevelopmentP20GM146584 · NIGMS · CLEMSON UNIVERSITY · PI JAMES Culvin MORRIS · 2022 to 2026
$13.5M
The role of acetate fermentation in Entamoeba histolytica growth and infectionP20GM109094 · NIGMS · CLEMSON UNIVERSITY · PI MORRIS, MEREDITH T · 2016 to 2020
$10.4M
NIAID NIH HHS HHSN272201700059CNIGMS NIH HHS P20 GM109094NIGMS NIH HHS P20 GM146584
6 · The paper itself

Abstract

Infection with pathogenic free-living amoebae, including Naegleria fowleri,

Indexed as

AcanthamoebaAmebiasisAmoebaBalamuthia mandrillarisNaegleria fowleriGlucokinaseHumansGlucokinaseAcanthamoeba castellaniiBalamuthia mandrillarisfree-living amoebaglucokinaseglycolysisinhibitorsNaegleria fowleripentose phosphate pathway

Identifiers

PMID35604214
PMCPMC9211422
OpenAlexW4281289023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.