Evidence map›Paper›PMID 35604096›Full record

ArticlemBio2022

The Transcription Factor Roc1 Is a Key Regulator of Cellulose Degradation in the Wood-Decaying Mushroom

Ioana M Marian, Peter Jan Vonk, Ivan D Valdes, Kerrie Barry, Benedict Bostock, Akiko Carver, Chris Daum, Harry Lerner, Anna Lipzen, Hongjae Park and 10 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The Zn(II)2Cys6 transcription factorApplied and environmental microbiology · 2026
    Article
  5. Article
  6. Article
  7. mBio · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Two ZnApplied and environmental microbiology · 2024
    Article
  14. Article
  15. Review
  16. Genome annotations for the ascomycete fungiMicrobiology resource announcements · 2024
    Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 3 countries.

Ioana M Marian *Microbiology, Department of Biology, Faculty of Science, Utrecht Universitygrid.5477.1, Utrecht, The Netherlands.
Peter Jan Vonk *Microbiology, Department of Biology, Faculty of Science, Utrecht Universitygrid.5477.1, Utrecht, The Netherlands.
Ivan D ValdesMicrobiology, Department of Biology, Faculty of Science, Utrecht Universitygrid.5477.1, Utrecht, The Netherlands.
Kerrie BarryU.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Benedict BostockMicrobiology, Department of Biology, Faculty of Science, Utrecht Universitygrid.5477.1, Utrecht, The Netherlands.
Akiko CarverU.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Chris DaumU.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Harry LernerMicrobiology, Department of Biology, Faculty of Science, Utrecht Universitygrid.5477.1, Utrecht, The Netherlands.
Anna LipzenU.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Hongjae ParkU.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Margo B P SchullerMicrobiology, Department of Biology, Faculty of Science, Utrecht Universitygrid.5477.1, Utrecht, The Netherlands.
Martin TegelaarMicrobiology, Department of Biology, Faculty of Science, Utrecht Universitygrid.5477.1, Utrecht, The Netherlands.
Andrew TrittU.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Jeremy SchmutzU.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Jane GrimwoodU.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Luis G LugonesMicrobiology, Department of Biology, Faculty of Science, Utrecht Universitygrid.5477.1, Utrecht, The Netherlands.
In-Geol ChoiU.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.ORCID 0000-0001-7403-6274
Han A B WöstenMicrobiology, Department of Biology, Faculty of Science, Utrecht Universitygrid.5477.1, Utrecht, The Netherlands.
Igor V GrigorievU.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Robin A OhmMicrobiology, Department of Biology, Faculty of Science, Utrecht Universitygrid.5477.1, Utrecht, The Netherlands.ORCID 0000-0003-2548-0074
Lawrence Berkeley National Laboratory · USUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wood-decaying fungi of the class Agaricomycetes (phylum Basidiomycota) are saprotrophs that break down lignocellulose and play an important role in nutrient recycling. They secrete a wide range of extracellular plant cell wall degrading enzymes that break down cellulose, hemicellulose, and lignin, the main building blocks of plant biomass. Although the production of these enzymes is regulated mainly at the transcriptional level, no activating regulators have been identified in any wood-decaying fungus in the class Agaricomycetes. We studied the regulation of cellulase expression in the wood-decaying fungus

Indexed as

AgaricalesBasidiomycotaCellulaseSchizophyllumCarbonCelluloseFungal ProteinsLigninTranscription FactorsCarbonCellulaseCelluloseFungal ProteinsLigninTranscription FactorsChIP-Seqcomparative genomicscomparative transcriptomicsfungigene regulationlignocellulose degradation

Identifiers

PMID35604096
PMCPMC9239231
OpenAlexW4281286344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.