Evidence map›Paper›PMID 35603899›Full record

ArticleNutrition and cancer2022

Fermented Soy Drink (Q-CAN® PLUS) Induces Apoptosis and Reduces Viability of Cancer Cells.

Xinshou Ouyang, Yonglin Chen, Boodapati S Tejaswi, Suyavaran Arumugam, Eric Secor, Theresa R Weiss, Michael Leapman, Ather Ali

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrition and cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xinshou OuyangDepartment of Internal Medicine (Digestive Diseases), Yale University School of Medicine, New Haven, CT, USA.
Yonglin ChenDepartment of Internal Medicine (Digestive Diseases), Yale University School of Medicine, New Haven, CT, USA.
Boodapati S TejaswiDepartment of Internal Medicine (Digestive Diseases), Yale University School of Medicine, New Haven, CT, USA.
Suyavaran ArumugamDepartment of Internal Medicine (Digestive Diseases), Yale University School of Medicine, New Haven, CT, USA.
Eric SecorHartford Hospital and University of Connecticut, Hartford, CT, USA.
Theresa R WeissDepartment of Pediatrics (General Pediatrics), Yale University School of Medicine, New Haven, CT, USA.
Michael LeapmanDepartment of Urology, Yale University School of Medicine, New Haven, CT, USA.
Ather AliDepartment of Pediatrics (General Pediatrics), Yale University School of Medicine, New Haven, CT, USA.
Yale University · USHartford Hospital · US

Funding

Yale Liver CenterP30DK034989 · NIDDK · YALE UNIVERSITY · PI WAJAHAT Zafar MEHAL · 1986 to 2026
$31.1M
NIDDK NIH HHS P30 DK034989
6 · The paper itself

Abstract

This study tested the ability of a fermented soy product to induce tumor cell toxicity and to assess if this was due to fermentation of soy, and to the genistein content. Four cancer cell lines were cultured without additive, with fermented soy (Q-CAN® PLUS), nonfermented soy, or genistein, and cell viability was examined at 24 h, 48 h, and 72 h. The sensitivity of the cell lines to apoptosis by Q-CAN PLUS was tested with the Annexin V assay. All cell lines demonstrated a dose and time response reduction in tumor cell viability with exposure to Q-CAN PLUS (IC

Indexed as

IsoflavonesNeoplasmsApoptosisCell Line, TumorCell SurvivalGenisteinGlycine maxGenisteinIsoflavones

Identifiers

PMID35603899
PMCPMC10986312
OpenAlexW4281286772

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.