ArticleAngewandte Chemie (International ed. in English)2022
Zinc-Catalyzed Enantioselective [3+2] Cycloaddition of Azomethine Ylides Using Planar Chiral [2.2]Paracyclophane-Imidazoline N,O-ligands.
Article in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- Planar Chirality Controls Diastereotopicity in [2.2]Paracyclophanyl Cyclopropenes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Delicate molecular design, self-assembly and functional applications of chiral cyclophanes.Chemical science · 2026Review
- Synthesis of heterocycles based on azomethine ylides from α-amino acids (or amines) and carbonyl compounds.Beilstein journal of organic chemistry · 2026Review
- Recent Developments in Azomethine Ylide-Initiated Double Cycloadditions.Molecules (Basel, Switzerland) · 2025Review
- Tunable Endo/Exo Selectivity in Direct Catalytic Asymmetric 1,3-Dipolar Cycloadditions with Polyfunctional Lewis Acid / Azolium-Aryloxide Catalysts.Angewandte Chemie (International ed. in English) · 2025Article
- Stereocontrolled Construction of Multi-Chiral [2.2]Paracyclophanes via Cobaltaphotoredox Dual Catalysis.ACS catalysis · 2025Article
- One-Step Maleimide-Based Dual Functionalization of Protein N-Termini.Angewandte Chemie (International ed. in English) · 2025Article
- Organocatalytic desymmetrization provides access to planar chiral [2.2]paracyclophanes.Nature communications · 2024Article
- Diverse Synthesis of Fused Polyheterocyclic Compounds via [3 + 2] Cycloaddition of In Situ-Generated HeteroaromaticMolecules (Basel, Switzerland) · 2023Article
- Electron-rich benzofulvenes as effective dipolarophiles in copper(i)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides.Chemical science · 2023Article
- Zinc-Catalyzed Enantioselective [3+2] Cycloaddition of Azomethine Ylides Using Planar Chiral [2.2]Paracyclophane-Imidazoline N,O-ligands.Angewandte Chemie (International ed. in English) · 2022Article
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Abstract
We present a facile synthetic route toward a novel series of imidazolinyl-[2.2]paracyclophanol (UCD-Imphanol) ligands possessing central and planar chirality. Both sets of diastereomeric ligands were successfully purified by column chromatography. The preliminary application of this family of ligands showed excellent activities in the asymmetric Zn-catalyzed azomethine ylide cycloaddition. Enantioenriched pyrrolidines, in a substrate scope of 20 examples, were accessed in high levels of endo/exo ratios (up to >99/1) and enantioselectivities (up to >99 % ee) with excellent yields (up to 99 %) by using (S,S,S
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