Evidence map›Paper›PMID 35603727›Full record

ArticleJournal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology2022

Analysis of serum placental growth factor levels in preeclamptic and normotensive pregnant women in Lagos, Nigeria: a worthwhile screening tool?

Ayodeji A Oluwole, Adeolu A Onakoya, Kehinde S Okunade, Ochuwa A Babah, Opeyemi Akinajo

Open access · greenAbstract read
In one paragraph

Article in Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ayodeji A OluwoleDepartment of Obstetrics and Gynaecology, College of Medicine, University of Lagos, Lagos, Nigeria.
Adeolu A OnakoyaDepartment of Obstetrics and Gynaecology, Lagos University Teaching Hospital, Lagos, Nigeria.
Kehinde S OkunadeDepartment of Obstetrics and Gynaecology, College of Medicine, University of Lagos, Lagos, Nigeria.ORCID 0000-0002-0957-7389
Ochuwa A BabahDepartment of Obstetrics and Gynaecology, College of Medicine, University of Lagos, Lagos, Nigeria.
Opeyemi AkinajoDepartment of Obstetrics and Gynaecology, Lagos University Teaching Hospital, Lagos, Nigeria.
University of Lagos · NGLagos University Teaching Hospital · NG

Funding

Neuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Ighovwerha Ofotokun · 2018 to 2026
$12.2M
Partnership for Global Health Research Training Program (Renewal)-Supplement for OBSSR, NCI, NCI-AIDS and NIDCDD43TW010543 · FIC · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Wafaie W Fawzi, DAVIDSON HOWES HAMER · 2017 to 2026
$12.1M
Building Research And Innovation in Nigeria's Science - (BRAINS)D43TW010134 · FIC · COLLEGE OF MEDICINE, UNIVERSITY OF LAGOS · PI OGUNSOLA, FOLASADE TOLULOPE · 2015 to 2020
$3.2M
Nigeria HIV Research Training ProgramD43TW010934 · FIC · EMORY UNIVERSITY · PI Ighovwerha Ofotokun · 2019 to 2026
$2.4M
FIC NIH HHS D43 TW010134FIC NIH HHS D43 TW010543FIC NIH HHS D43 TW010934NIA NIH HHS U54 AG062334
6 · The paper itself

Abstract

The clinical usefulness of serum placental growth factor (PlGF) as a predictive biomarker of preeclampsia is currently being examined. However, there are still conflicting results in the literature. We assessed the association between maternal low PlGF levels and the occurrence and severity of preeclampsia. This was an analytical cross-sectional study conducted among 60 women with preeclampsia, and an equal number of matched normotensive pregnant women. PlGF concentrations were analysed using the ELISA method. Bivariate and multivariate analysis was used to test for the association between low maternal PlGF levels and the occurrence of preeclampsia and its severity. Statistical significance was reported at

Indexed as

Pre-EclampsiaBiomarkersCross-Sectional StudiesFemaleGravidityHumansNigeriaPlacentaPlacenta Growth FactorPregnancyPregnant PeopleVascular Endothelial Growth Factor Receptor-1BiomarkersPGF protein, humanPlacenta Growth FactorVascular Endothelial Growth Factor Receptor-1BiomarkerELISALagosNigeriaPlGFpreeclampsia

Identifiers

PMID35603727
PMCPMC9843609
OpenAlexW4281387001

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.