Evidence map›Paper›PMID 35603666›Full record

ArticleNeurodegenerative disease management2022

The 5-Cog paradigm to improve detection of cognitive impairment and dementia: clinical trial protocol.

Rachel Chalmer, Emmeline Ayers, Erica F Weiss, Rubina Malik, Amy Ehrlich, Cuiling Wang, Jessica Zwerling, Asif Ansari, Katherine L Possin, Joe Verghese

Open access · greenAbstract readClinical Trial Protocol
In one paragraph

Article in Neurodegenerative disease management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
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  5. "Cognitive" Criteria in Older Adults With Slow Gait Speed: Implications for Motoric Cognitive Risk Syndrome.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Rachel ChalmerDepartment of Medicine, Division of Geriatrics, Montefiore Medical Center & Albert Einstein College of Medicine, Bronx, NY 10467, USA.ORCID 0000-0001-6394-6539
Emmeline AyersDepartment of Neurology, Montefiore Medical Center & Albert Einstein College of Medicine, Bronx, NY 10467, USA.
Erica F WeissDepartment of Neurology, Montefiore Medical Center & Albert Einstein College of Medicine, Bronx, NY 10467, USA.ORCID 0000-0002-0726-7547
Rubina MalikDepartment of Medicine, Division of Geriatrics, Montefiore Medical Center & Albert Einstein College of Medicine, Bronx, NY 10467, USA.
Amy EhrlichDepartment of Medicine, Division of Geriatrics, Montefiore Medical Center & Albert Einstein College of Medicine, Bronx, NY 10467, USA.
Cuiling WangDepartment of Epidemiology & Population Health, Montefiore Medical Center & Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Jessica ZwerlingDepartment of Neurology, Montefiore Medical Center & Albert Einstein College of Medicine, Bronx, NY 10467, USA.
Asif AnsariDepartment of Medicine, Division of Geriatrics, Montefiore Medical Center & Albert Einstein College of Medicine, Bronx, NY 10467, USA.
Katherine L PossinDepartment of Neurology, Memory & Aging Center, University of California San Francisco, San Francisco, CA 94158, USA.
Joe VergheseDepartment of Medicine, Division of Geriatrics, Montefiore Medical Center & Albert Einstein College of Medicine, Bronx, NY 10467, USA.
Albert Einstein College of Medicine · USUniversity of California, San Francisco · US

Funding

CTSA Administrative Supplement for Informatics Core: A novel AI/ML system to predict respiratory failure and ARDS in Covid-19 patientsUL1TR002556 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, KIM, MIMI Y · 2018 to 2022
$26.7M
Cognitive sequelae of the biological effects of COVID-19 on the nervous system in a health disparity populationUH3NS105565 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI VERGHESE, JOE · 2019 to 2021
$2.8M
5-Cog Battery to improve detection of cognitive impairment and dementiaUG3NS105565 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI VERGHESE, JOE · 2017 to 2018
$1.4M
NCATS NIH HHS UL1 TR002556NINDS NIH HHS UG3 NS105565NINDS NIH HHS UH3 NS105565
6 · The paper itself

Abstract

Cognitive impairment related to dementia is under-diagnosed in primary care despite availability of numerous cognitive assessment tools; under-diagnosis is more prevalent for members of racial and ethnic minority groups. Clinical decision-support systems may improve rates of primary care providers responding to positive cognitive assessments with appropriate follow-up. The 5-Cog study is a randomized controlled trial in 1200 predominantly Black and Hispanic older adults from an urban underserved community who are presenting to primary care with cognitive concerns. The study will validate a novel 5-minute cognitive assessment coupled with an electronic medical record-embedded decision tree to overcome the barriers of current cognitive assessment paradigms in primary care and facilitate improved dementia care.

Indexed as

Cognitive DysfunctionDementiaAgedEthnicityHumansMinority GroupsRandomized Controlled Trials as Topicclinical trial protocolcognitive assessmentcognitive impairmentcognitive screeningdementiadissemination and implementation sciencerandomized controlled trial

Identifiers

PMID35603666
PMCPMC9245592
OpenAlexW4281400087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.