Evidence map›Paper›PMID 35603658›Full record

ArticleEuropean journal of heart failure2022

Prognostic impact of the updated 2018 HFA-ESC definition of advanced heart failure: results from the HELP-HF registry.

Matteo Pagnesi, Carlo Mario Lombardi, Mauro Chiarito, Davide Stolfo, Luca Baldetti, Ferdinando Loiacono, Chiara Tedino, Luca Arrigoni, Daniele Ghiraldin, Daniela Tomasoni and 14 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Gut microbiota's role in heart failure.Heart failure reviews · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Observational
  12. 2024 update in heart failure.ESC heart failure · 2025
    Review
  13. Review
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 7 institutions in 1 country.

Matteo PagnesiInstitute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Carlo Mario LombardiInstitute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Mauro ChiaritoHumanitas Research Hospital IRCCS, Rozzano (MI), Italy.
Davide StolfoCardiovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI), University of Trieste, Trieste, Italy.
Luca BaldettiCardiac Intensive Care Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Ferdinando LoiaconoHumanitas Research Hospital IRCCS, Rozzano (MI), Italy.
Chiara TedinoInstitute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Luca ArrigoniInstitute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Daniele GhiraldinInstitute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Daniela TomasoniInstitute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Riccardo Maria InciardiInstitute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Marta MaccalliniHumanitas Research Hospital IRCCS, Rozzano (MI), Italy.
Alessandro VillaschiHumanitas Research Hospital IRCCS, Rozzano (MI), Italy.
Gaia GaspariniHumanitas Research Hospital IRCCS, Rozzano (MI), Italy.
Marco MontellaHumanitas Research Hospital IRCCS, Rozzano (MI), Italy.
Stefano ContessiCardiovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI), University of Trieste, Trieste, Italy.
Daniele CocianniCardiovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI), University of Trieste, Trieste, Italy.
Maria PerottoCardiovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI), University of Trieste, Trieste, Italy.
Giuseppe BaroneCardiac Intensive Care Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Marco MerloCardiovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI), University of Trieste, Trieste, Italy.
Alberto Maria CappellettiCardiac Intensive Care Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Gianfranco SinagraCardiovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI), University of Trieste, Trieste, Italy.
Daniela PiniHumanitas Research Hospital IRCCS, Rozzano (MI), Italy.
Marco MetraInstitute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
University of Brescia · ITIRCCS Humanitas Research Hospital · ITUniversity of Trieste · ITAzienda Sanitaria Universitaria Integrata di Trieste · ITHumanitas University · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto di Ricovero e Cura a Carattere Scientifico San Raffaele

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe Heart Failure Association of the European Society of Cardiology (HFA-ESC) proposed a definition of advanced heart failure (HF) that has not been validated, yet. We assessed its prognostic impact in a consecutive series of patients with high-risk HF. METHODS AND

resultsThe HELP-HF registry enrolled consecutive patients with HF and at least one high-risk 'I NEED HELP' marker, evaluated at four Italian centres between 1

conclusionsThe HFA-ESC advanced HF definition had a strong prognostic impact in a contemporary, real-world, multicentre high-risk cohort of patients with HF.

Indexed as

CardiologyHeart FailureAgedAged, 80 and overFemaleHumansMaleMiddle AgedPrognosisRegistriesStroke VolumeVentricular Function, LeftAdvanced heart failureEuropean Society Of CardiologyHeart failureHeart Failure AssociationHospitalizationMortality

Identifiers

PMID35603658
PMCPMC9796314
OpenAlexW4281396363

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.