Evidence map›Paper›PMID 35603455›Full record

Observational studyEmerging microbes & infections2022

Identification of circulating microRNA profiles associated with pulmonary function and radiologic features in survivors of SARS-CoV-2-induced ARDS.

María C García-Hidalgo, Jessica González, Iván D Benítez, Paola Carmona, Sally Santisteve, Manel Pérez-Pons, Anna Moncusí-Moix, Clara Gort-Paniello, Fátima Rodríguez-Jara, Marta Molinero and 18 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Emerging microbes & infections, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 4 institutions in 2 countries.

María C García-HidalgoTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
Jessica GonzálezTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
Iván D BenítezTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
Paola CarmonaTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
Sally SantisteveTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
Manel Pérez-PonsTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
Anna Moncusí-MoixTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
Clara Gort-PanielloTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
Fátima Rodríguez-JaraTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
Marta MolineroTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
Thalia BelmonteTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
Gerard TorresTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
Gonzalo LabarcaMolecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Faculty of Pharmacy, Universidad de Concepcion, Concepcion, Chile.
Estefania Nova-LampertiMolecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Faculty of Pharmacy, Universidad de Concepcion, Concepcion, Chile.
Jesús CaballeroGrup de Recerca Medicina Intensiva, Intensive Care Department Hospital Universitari Arnau de Vilanova, IRBLleida, Lleida, Spain.
Jesús F Bermejo-MartinCIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain.
Adrián CeccatoCIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain.
Laia Fernández-BaratCIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain.ORCID 0000-0001-7528-9636
Ricard FerrerCIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain.ORCID 0000-0002-4859-4747
Dario Garcia-GasullaBarcelona Supercomputing Center (BSC), Barcelona, Spain.
Rosario MenéndezCIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain.
Ana MotosCIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain.
Oscar PeñuelasCIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain.
Jordi RieraCIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain.
Antoni TorresCIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain.ORCID 0000-0002-8643-2167
Ferran BarbéTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
David de Gonzalo-CalvoTranslational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.ORCID 0000-0003-2240-3532
CIBERESUCICOVID Project (COV20/00110, ISCIII)Translational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.
Instituto de Salud Carlos III · ESHospital Universitari Arnau de Vilanova · ESUniversity of Concepción · CLBarcelona Supercomputing Center · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a limited understanding of the pathophysiology of postacute pulmonary sequelae in severe COVID-19. The aim of current study was to define the circulating microRNA (miRNA) profiles associated with pulmonary function and radiologic features in survivors of SARS-CoV-2-induced ARDS. The study included patients who developed ARDS secondary to SARS-CoV-2 infection (n = 167) and a group of infected patients who did not develop ARDS (n = 33). Patients were evaluated 3 months after hospital discharge. The follow-up included a complete pulmonary evaluation and chest computed tomography. Plasma miRNA profiling was performed using RT-qPCR. Random forest was used to construct miRNA signatures associated with lung diffusing capacity for carbon monoxide (D

Indexed as

Circulating MicroRNACOVID-19Respiratory Distress SyndromeHumansLungMicroRNAsSARS-CoV-2SurvivorsCirculating MicroRNAMicroRNAsMIRN495 microRNA, humanAcute respiratory distress syndromeCOVID-19lung functionmicroRNAsequelaetotal severity score

Identifiers

PMID35603455
PMCPMC9176679
OpenAlexW4281291832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.