Evidence map›Paper›PMID 35603280›Full record

ArticleCommunications medicine2022

A 2-month field cohort study of SARS-CoV-2 in saliva of BNT162b2 vaccinated nursing home workers.

Claude Saegerman, Anh Nguyet Diep, Véronique Renault, Anne-Françoise Donneau, Lambert Stamatakis, Wouter Coppieters, Fabienne Michel, Christophe Breuer, Margaux Dandoy, Olivier Ek and 9 more

Open access · goldAbstract read
In one paragraph

Article in Communications medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Towards deployable CRISPR-based nucleic acid detection.Progress in biomedical engineering (Bristol, England) · 2026
    Review
  2. Article
  3. Article
  4. Diagnosis ofPathogens (Basel, Switzerland) · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 1 institution in 1 country.

Claude SaegermanFundamental and Applied Research for Animal and Health (FARAH) Center, Liège University, Liège, Belgium.ORCID 0000-0001-9087-7436
Anh Nguyet DiepBiostatistics Unit, Liège University, Liège, Belgium.ORCID 0000-0001-5134-3220
Véronique RenaultFundamental and Applied Research for Animal and Health (FARAH) Center, Liège University, Liège, Belgium.
Anne-Françoise DonneauRisk Assessment Group COVID-19, Liège University, Liège, Belgium.
Lambert StamatakisGeneral Delegation COVID-19, Government of the Walloon Region, Namur, Belgium.
Wouter CoppietersUnit of Animal Genomics, GIGA Institute, Liège University, Liège, Belgium.
Fabienne MichelCollection and Analysis of Data and Information of Strategic Utility (RADIUS), Liège University, Liège, Belgium.
Christophe BreuerLiège University, Liège, Belgium.
Margaux DandoyCovid-19 Platform of Liège University, Liège, Belgium.
Olivier EkCovid-19 Platform of Liège University, Liège, Belgium.
Claire GourzonesCovid-19 Platform of Liège University, Liège, Belgium.
Joey SchynsCovid-19 Platform of Liège University, Liège, Belgium.
Emeline GoffinCovid-19 Platform of Liège University, Liège, Belgium.
Frédéric MinnerCovid-19 Platform of Liège University, Liège, Belgium.
Keith DurkinLaboratory of Human Genetics, GIGA Research Institute, Liège, Belgium.ORCID 0000-0001-7475-6618
Maria ArtesiLaboratory of Human Genetics, GIGA Research Institute, Liège, Belgium.
Vincent BoursLaboratory of Human Genetics, GIGA Research Institute, Liège, Belgium.
Fabrice Bureau *Covid-19 Platform of Liège University, Liège, Belgium.
Laurent Gillet *Fundamental and Applied Research for Animal and Health (FARAH) Center, Liège University, Liège, Belgium.
University of Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Nursing home (NH) residents have been severely affected during the COVID-19 pandemic because of their age and underlying comorbidities. Infection and outbreaks in NHs are most likely triggered by infected workers. Screening for asymptomatic NH workers can prevent risky contact and viral transmission to the residents. This study examined the effect of the BNT162b2 mRNA COVID‑19 (Comirnaty Methods: A 2-month cohort study was conducted among 99 NHs in the Walloon region (Belgium), at the start of February 2021. Three groups of workers, i.e., non-vaccinated ( Results: The protection fraction against the excretion of the SARS-CoV-2 in the saliva samples of the workers after the second dose is estimated at 0.90 (95% CI: 0.18; 0.99) at 1 week and 0.83 (95% CI: 0.54; 0.95) at 8 weeks. We observe more circulating SARS-CoV-2 and a greater variability of viral loads in the unvaccinated group compared to those of the vaccinated group. Conclusions: This field cohort study advances our knowledge of the efficacy of the mRNA BNT162b2 COVID-19 vaccine on the viral shedding in the saliva specimens of vaccinated NH workers, contributing to better decision-making in public health interventions and management.

Indexed as

EpidemiologyRNA vaccines

Identifiers

PMID35603280
PMCPMC9053279
OpenAlexW4205445891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.