Evidence map›Paper›PMID 35603175›Full record

ArticleFrontiers in immunology2022

FOXO Dictates Initiation of B Cell Development and Myeloid Restriction in Common Lymphoid Progenitors.

Lucía Peña-Pérez, Shabnam Kharazi, Nicolai Frengen, Aleksandra Krstic, Thibault Bouderlique, Julia Hauenstein, Minghui He, Ece Somuncular, Xiaoze Li Wang, Carin Dahlberg and 10 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Determination ofFrontiers in toxicology · 2024
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 1 country.

Lucía Peña-PérezCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Shabnam KharaziCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Nicolai FrengenCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Aleksandra KrsticCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Thibault BouderliqueCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Julia HauensteinCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Minghui HeDepartment of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Ece SomuncularCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Xiaoze Li WangCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Carin DahlbergDepartment of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Charlotte GustafssonCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Ann-Sofie JohanssonCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Julian WalfridssonCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Nadir KadriDepartment of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
Petter WollCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Marcin KierczakDepartment of Cell and Molecular Biology, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Hong QianCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Lisa WesterbergDepartment of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Sidinh LucCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Robert MånssonCenter for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Karolinska Institutet · SEScience for Life Laboratory · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of B cells relies on an intricate network of transcription factors critical for developmental progression and lineage commitment. In the B cell developmental trajectory, a temporal switch from predominant

Indexed as

HematopoiesisLymphoid Progenitor CellsB-LymphocytesForkhead Box Protein O1Precursor Cells, B-LymphoidForkhead Box Protein O1B cellFOXO (forkhead box protein O)gene regulationlineage commitment/specificationmyeloid restriction

Identifiers

PMID35603175
PMCPMC9116193
OpenAlexW4229032341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.