Evidence map›Paper›PMID 35603158›Full record

ArticleFrontiers in immunology2022

LRBA Deficiency Can Lead to Lethal Colitis That Is Diminished by SHIP1 Agonism.

Raki Sudan, Sandra Fernandes, Neetu Srivastava, Chiara Pedicone, Shea T Meyer, John D Chisholm, Robert W Engelman, William G Kerr

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. ILC3: a case of conflicted identity.Frontiers in immunology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Raki SudanDepartment of Microbiology and Immunology, SUNY Upstate Medical University, Syracuse, NY, United States.
Sandra FernandesDepartment of Microbiology and Immunology, SUNY Upstate Medical University, Syracuse, NY, United States.
Neetu SrivastavaDepartment of Microbiology and Immunology, SUNY Upstate Medical University, Syracuse, NY, United States.
Chiara PediconeDepartment of Microbiology and Immunology, SUNY Upstate Medical University, Syracuse, NY, United States.
Shea T MeyerDepartment of Chemistry, Syracuse University, Syracuse, NY, United States.
John D ChisholmDepartment of Chemistry, Syracuse University, Syracuse, NY, United States.
Robert W EngelmanDepartment of Pathology and Cell Biology, University of South Florida, Tampa, FL, United States.
William G KerrDepartment of Microbiology and Immunology, SUNY Upstate Medical University, Syracuse, NY, United States.
SUNY Upstate Medical University · USSyracuse University · USUniversity of South Florida · US

Funding

Translating SHIP1 Genetics to Generate a Novel Alzheimers Pharmacologic AgentRF1AG059717 · NIA · UNIVERSITY OF KENTUCKY · PI ESTUS, STEVEN, HUMPHREY, MARY BETH · 2018 to 2019
$3.9M
NIA NIH HHS RF1 AG059717
6 · The paper itself

Abstract

Humans homozygous for inactivating

Indexed as

ColitisCommon Variable ImmunodeficiencyAdaptor Proteins, Signal TransducingAnimalsMiceMutationT-Lymphocytes, RegulatoryAdaptor Proteins, Signal TransducingLrba protein, mousecolitisILC3 cytokinesLRBA deficiencySHIP1src homology 2 domain-containing inositol phosphatase 1

Identifiers

PMID35603158
PMCPMC9116273
OpenAlexW4225397309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.