ArticleOpen veterinary journal
Suppression of reproductive function in juvenile rams by a slow-release gonadotropin-releasing hormone implant.
Article in Open veterinary journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- GnRH Immunocastration in Male Xizang Sheep: Impacts on Rumen Microbiome and Metabolite Profiles for Enhanced Health and Productivity.Animals : an open access journal from MDPI · 2024Article
- Systematic review of hormonal strategies to improve fertility in rams.Animal reproduction · 2024Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Regarding animal welfare and reversible suppression of reproduction the need for alternatives to surgical castration, like slow-release gonadotropin-releasing hormone (GnRH) implants, is increasing. Aim: In this study, we evaluated whether the onset of puberty can be suppressed by implantation of a slow-release GnRH implant (4.7 mg deslorelin) in juvenile rams. Methods: Seven juvenile rams (3-5.5 months) were treated with the GnRH analog deslorelin to analyze the effects on testicular development, sonographic findings of testicular tissue, testosterone concentration in the blood, spermatogenesis, and sperm parameters from the epididymis after castration. Seven rams of the same age without an implant served as controls. Results: Follow-up examinations were conducted over 5 months, after which four rams per group were castrated. No significant group differences were found in the andrological parameters on the group level, but testicular development was suppressed in three rams in the treated group. Histological examination revealed spermatogenesis in the testicular tissue in three of four animals treated with a GnRH analog. Conclusion: The onset of puberty in juvenile rams cannot be reliably suppressed by using the slow-release GnRH implant Suprelorin®.
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Registered trials
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