Evidence map›Paper›PMID 35602835›Full record

ReviewCureus2022

Probiotics in Irritable Bowel Syndrome: A Review of Their Therapeutic Role.

Lakshmi Satish Kumar, Lakshmi Sree Pugalenthi, Mahlika Ahmad, Sanjana Reddy, Zineb Barkhane, Jalal Elmadi

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Functional Yogurt Enriched withMolecules (Basel, Switzerland) · 2026
    Article
  6. ImmobilizedMicroorganisms · 2026
    Article
  7. Review
  8. Review
  9. An 8-Week Course of Bifidobacterium longum 35624Probiotics and antimicrobial proteins · 2025
    Observational
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 5 countries.

Lakshmi Satish KumarInternal Medicine, University of Perpetual Help System DALTA, Manila, PHL.
Lakshmi Sree PugalenthiInternal Medicine, Bicol Christian College of Medicine, Legazpi City, PHL.
Mahlika AhmadResearch, Ziauddin University, Karachi, PAK.
Sanjana ReddyMedicine, Bogomolets National Medical University, Kiev, UKR.
Zineb BarkhaneResearch, Faculty of Medicine and Pharmacy of Casablanca, Université Hassan II de Casablanca, Casablanca, MAR.
Jalal ElmadiFaculty of Medical Sciences, Universidad Nacional Autónoma de Honduras, Tegucigalpa, HND.
University of Perpetual Help System DALTA · PHZiauddin University · PKBogomolets National Medical University · UAUniversity of Santo Tomas–Legazpi · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irritable bowel syndrome (IBS) is a chronic collection of symptoms and lowers the quality of life. The management of such patients has always involved mitigating the symptoms produced by this disorder. This article reviews the role of probiotics in IBS by compiling various studies to deduce the possible symptomatic relief that probiotics may provide to IBS patients. Given the encouraging part of probiotics in abundant other gastrointestinal conditions, this article focuses on understanding the specific functional effects (if any) that are brought about by adding probiotics in patients with different types of IBS such as IBS with predominant constipation, IBS with predominant diarrhea, and even the unclassified type of IBS. The purpose of analyzing the role of probiotics is to study the changes brought about by them at the level of the gut microbiota in patients suffering from IBS, as this may prove to be of prime importance in managing such conditions with time. This article has also furnished an overview of the pathogenesis, diagnostic criteria, treatment modalities, sources of probiotics, and their therapeutic significance in IBS patients.

Indexed as

bloatingflatulencefodmapsgastrointestinalirritable bowel syndromemicrobiomeprobioticsrome iv criteriastool frequencysymptomatic relief

Identifiers

PMID35602835
PMCPMC9116469
OpenAlexW4224246577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.