Evidence map›Paper›PMID 35602514›Full record

ArticleFrontiers in medicine2022

Contrasting Association Between COVID-19 Vaccine Hesitancy and Mental Health Status in India and Saudi Arabia-A Preliminary Evidence Collected During the Second Wave of COVID-19 Pandemic.

Saikarthik Jayakumar, Saraswathi Ilango, Senthil Kumar K, Abdullah Alassaf, Abdullah Aljabr, Anand Paramasivam, Suresh Mickeymaray, Yazeed Mohammed Hawsah, Ahmed Saad Aldawish

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Saikarthik JayakumarDepartment of Basic Medical Sciences, College of Dentistry, Majmaah University, Al Majma'ah, Saudi Arabia.
Saraswathi IlangoDepartment of Physiology, Madha Medical College and Research Institute, Chennai, India.
Senthil Kumar KDepartment of Physiology, Madha Medical College and Research Institute, Chennai, India.
Abdullah AlassafDepartment of Preventive Dental Science, College of Dentistry, Majmaah University, Al Majma'ah, Saudi Arabia.
Abdullah AljabrDepartment of Medical Education, College of Dentistry, Majmaah University, Al Majma'ah, Saudi Arabia.
Anand ParamasivamDepartment of Basic Medical Sciences, College of Dentistry, Majmaah University, Al Majma'ah, Saudi Arabia.
Suresh MickeymarayDepartment of Biology, College of Science, Majmaah University, Al Majma'ah, Saudi Arabia.
Yazeed Mohammed HawsahCollege of Dentistry, Majmaah University, Al Majma'ah, Saudi Arabia.
Ahmed Saad AldawishCollege of Dentistry, Majmaah University, Al Majma'ah, Saudi Arabia.
Majmaah University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vaccine hesitancy is a global public health threat. Understanding the role of psychological factors in vaccine hesitancy is often neglected and relatively less explored. Aim and Objectives: To analyze the relationship between mental health and COVID-19 vaccine hesitancy before and after the advent of COVID-19 vaccines (AC19V) in the general population of India and Saudi Arabia (KSA) which vary in severity of the pandemic and vaccine mandates. Materials and Methods: A total of 677 adult participants from India and KSA participated in this cross-sectional online web-based survey. Sociodemographic details and current COVID-19 status pertaining to infection and vaccination were collected. Depression, anxiety, post-traumatic stress disorder (PTSD) symptoms, and perceptive need for mental health support (MHS) were assessed before and after AC19V. A newly constructed and validated COVID19 vaccine hesitancy scale-12 (COVID19-VHS12) scale was used to evaluate the COVID-19 vaccine hesitancy. Results: Prevalence and levels of depression and anxiety symptoms decreased significantly in Saudis but not in Indians after AC19V. PTSD symptoms showed a significant reduction in both India and KSA. Anxiety symptoms were higher in KSA than India before AC19V while PTSD was higher in India before and after AC19V. Except for the place of residence and employment status, the subgroups of sociodemographic variables which were at higher risk of negative mental health before AC19V showed improvement in their mental health after AC19V. The prevalence of COVID-19 vaccine hesitancy in India and KSA was 50.8% (95% CI 45.73-55.89%) and 55.7% (95% CI 50.16-61.31%), respectively. A bidirectional association between vaccine hesitancy and mental health was observed in KSA but not in India. Higher vaccine hesitancy favored higher levels of depression, anxiety, and perceptive need for MHS and vice versa in KSA. None of the mental health parameters predicted vaccine hesitancy in India, while higher vaccine hesitancy increased the risk of anxiety. Conclusion: Vaccine hesitancy has a negative impact on mental health and vice versa over and above the impact of sociodemographic factors and COVID-19 vaccination and infection status which shows variations between India and KSA.

Indexed as

anxietyCOVID-19 vaccine hesitancy scaleCOVID-19 vaccinesdepressionmental healthmental health supportPTSDvaccine hesitancy

Identifiers

PMID35602514
PMCPMC9116149
OpenAlexW4225412354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.