Evidence map›Paper›PMID 35602338›Full record

SynthesisComputational and mathematical methods in medicine2022

Meta-Analysis of the Diagnostic Value of Tracer Staining Technology Based on Nanocarbon Suspension in Sentinel Lymph Node Biopsy of Breast Cancer.

Luhua Xia, Le Chong, Zinan Lu, Xinhua Wang, Zhanfei Dong, Yanping Zhao, Cheng Chang, Gang Sun

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luhua XiaDepartment of Nuclear Medicine, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830011, China.
Le ChongDepartment of Ultrasonography, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830011, China.
Zinan LuDepartment of Radiotherapy, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830011, China.
Xinhua WangDepartment of Nuclear Medicine, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830011, China.
Zhanfei DongDepartment of Nuclear Medicine, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830011, China.
Yanping ZhaoDepartment of Nuclear Medicine, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830011, China.
Cheng ChangDepartment of Nuclear Medicine, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830011, China.
Gang SunDepartment of Breast and Thyroid Surgery, The Affiliated Cancer Hospital of Xinjiang Medical University, Xinjiang Cancer Center/Key Laboratory of Oncology of Xinjiang Uyghur Autonomous Region, Urumqi, Xinjiang 830011, China.ORCID https://orcid.org/0000-0002-1862-2268

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the diagnostic value of the nanometer carbon suspension tracer staining technique in sentinel lymph node biopsy of breast cancer is the objective of this study. Methods: The PubMed, Embase, Cochrane Library (Central), and Web of Science (SCI Expanded), and Chinese databases (CNKI, VIP, Wan Fang, and CBM) were systematically searched for studies on the diagnostic value of nanocarbon suspension in sentinel lymph node biopsy of breast cancer. Two reviewers independently assessed the methodological quality of each study using the QUADAS-2 tool. The extracted valid data were calculated using Meta-Disc1.4 software and tested for heterogeneity. STATA14.0 software was selected for sensitivity analysis of the included studies, and publication bias was assessed using Deeks' forest plot asymmetry test. Results: A total of 10 studies were obtained. The pooled data were as follows: sensitivity, 0.92 (0.88~0.95); specificity, 0.99 (0.98~1.00); positive likelihood ratio, 69.24 (30.34~158.02); negative likelihood ratio, 0.09 (0.06~0.13); and the combined diagnostic odds ratio, 747.40 (285.77~1954.76), AUC = 0.9881. Nanocarbon suspension tracers have an accuracy rate of 98.81% in the diagnosis of sentinel lymph nodes in breast cancer. Conclusion: Tracer staining technology based on nanocarbon suspension can accurately assess the status of lymph nodes in sentinel lymph node biopsy of breast cancer and has good stability and operability, which is worthy of clinical promotion.

Indexed as

Breast NeoplasmsSentinel Lymph NodeFemaleHumansLymph NodesSentinel Lymph Node BiopsyStaining and LabelingTechnology

Identifiers

PMID35602338
PMCPMC9119750

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.