Evidence map›Paper›PMID 35602311›Full record

ArticleInnovation in aging2022

Investing in Late-Life Brain Capital.

Walter D Dawson, Erin Smith, Laura Booi, Maia Mosse, Helen Lavretsky, Charles F Reynolds, Jeffrey Cummings, Patrick Brannally, William Hynes, Eric J Lenze and 15 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Innovation in aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Life-Course Brain Health as a Determinant of Late-Life Mental Health: American Association for Geriatric Psychiatry Expert Panel Recommendations.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2023
    Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors.

Walter D DawsonDepartment of Neurology, School of Medicine, Oregon Health & Science University, Portland, Oregon, USA.
Erin SmithGlobal Brain Health Institute at University of California, San Francisco (UCSF), San Francisco, California, USA.
Laura BooiGlobal Brain Health Institute at University of California, San Francisco (UCSF), San Francisco, California, USA.
Maia MosseDepartment of Medicine, Stanford Hospital, Stanford, California, USA.
Helen LavretskySemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA), Los Angeles, California, USA.
Charles F ReynoldsDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Jeffrey CummingsChambers-Grundy Center for Transformative Neuroscience, Department of Brain Health, School of Integrated Health Sciences, University of Nevada, Las Vegas, Las Vegas, Nevada, USA.
Patrick BrannallyAlzheimer's Disease Data Initiative, Gates Ventures, Redwood City, California, USA.
William HynesDepartment of Medicine, Stanford Hospital, Stanford, California, USA.
Eric J LenzeDepartment of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA.
Facundo ManesInstitute of Cognitive and Translational Neuroscience (INCYT), INECO Foundation, Favaloro University, Buenos Aires, Argentina.
Rym AyadiEuro-Mediterranean Economists Association, Barcelona, Spain.
Lori FrankRAND Corporation, Arlington, Virginia, USA.
Sandra Bond ChapmanCenter for BrainHealth®, The University of Texas at Dallas, Dallas, Texas, USA.
Ian H RobertsonGlobal Brain Health Institute at University of California, San Francisco (UCSF), San Francisco, California, USA.
Lori RubensteinAustralian Research Alliance for Children and Youth (ARACY), Canberra, Australian Capital Territory, Australia.
Jorge JraissatiIESE Center for Public Leadership and Government, IESE Business School, Madrid, Spain.
Agustin IbáñezGlobal Brain Health Institute at University of California, San Francisco (UCSF), San Francisco, California, USA.
Howard FillitAlzheimer's Drug Discovery Foundation (ADDF), New York City, New York, USA.
Dilip V JesteDepartments of Psychiatry and Neurosciences, University of California San Diego, La Jolla, California, USA.ORCID https://orcid.org/0000-0002-1161-7351
Anitha RaoNeurocern, Chicago, Illinois, USA.
Michael BerkIMPACT, the Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, Victoria, Australia.ORCID https://orcid.org/0000-0002-5554-6946
Eric A StorchDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, USA.
Antonella Santuccione ChadhaBiogen, Cambridge, Massachusetts, USA.
Harris A EyreIMPACT, the Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, Victoria, Australia.

Funding

Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KEVIN M DUFF, Lisa C Silbert · 2020 to 2026
$28.6M
Research Education ComponentP30AG072980 · NIA · BANNER HEALTH · PI HEATHER Allyson BIMONTE-NELSON · 2021 to 2026
$24.9M
Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) CNTN - ResubmissionP20GM109025 · NIGMS · CLEVELAND CLINIC FOUNDATION · PI Robert J. Fox, Jefferson Kinney · 2015 to 2026
$22.8M
Chronic Traumatic Encephalopathy: Detection, Diagnosis, Course, and Risk FactorsU01NS093334 · NINDS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CUMMINGS, JEFFREY L., REIMAN, ERIC MICHAEL · 2016 to 2022
$17.0M
Preclinical and Clincial OutcomesP50HD103555 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MIRJANA MALETIC-SAVATIC · 2020 to 2026
$9.9M
NVEDARC Clinical CoreP20AG068053 · NIA · CLEVELAND CLINIC FOUNDATION · PI WINT, DYLAN · 2020 to 2022
$3.3M
Alzheimer's Clinical Trial InnOvatioN (ACTION) InitiativeR35AG071476 · NIA · UNIVERSITY OF NEVADA LAS VEGAS · PI CUMMINGS, JEFFREY L. · 2021 to 2025
$2.9M
NIA NIH HHS P30 AG066518NIA NIH HHS P30 AG072980NIA NIH HHS R35 AG071476NICHD NIH HHS P50 HD103555NIGMS NIH HHS P20 GM109025NINDS NIH HHS U01 NS093334
6 · The paper itself

Abstract

Within many societies and cultures around the world, older adults are too often undervalued and underappreciated. This exacerbates many key challenges that older adults may face. It also undermines the many positive aspects of late life that are of tremendous value at both an individual and societal level. We propose a new approach to elevate health and well-being in late life by optimizing late-life Brain Capital. This form of capital prioritizes brain skills and brain health in a brain economy, which the challenges and opportunities of the 21st-century demands. This approach incorporates investing in late-life Brain Capital, developing initiatives focused on building late-life Brain Capital.

Indexed as

AgingBrain healthInnovationMental disordersNeurosciencePsychiatry

Identifiers

PMID35602311
PMCPMC9116879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.