Evidence map›Paper›PMID 35602184›Full record

ArticleCommunications medicine2021

Adherence and sustainability of interventions informing optimal control against the COVID-19 pandemic.

Laura Di Domenico, Chiara E Sabbatini, Pierre-Yves Boëlle, Chiara Poletto, Pascal Crépey, Juliette Paireau, Simon Cauchemez, François Beck, Harold Noel, Daniel Lévy-Bruhl and 1 more

Abstract read
In one paragraph

Article in Communications medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Comparative evaluation of behavioral epidemic models using COVID-19 data.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  12. Spatial and seasonal determinants of Lyme borreliosis incidence in France, 2016 to 2021.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  13. Article
  14. Global patterns and drivers of influenza decline during the COVID-19 pandemic.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
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  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Laura Di Domenico *INSERM, Sorbonne Université, Pierre Louis Institute of Epidemiology and Public Health, Paris, France.
Chiara E Sabbatini *INSERM, Sorbonne Université, Pierre Louis Institute of Epidemiology and Public Health, Paris, France.
Pierre-Yves BoëlleINSERM, Sorbonne Université, Pierre Louis Institute of Epidemiology and Public Health, Paris, France.
Chiara PolettoINSERM, Sorbonne Université, Pierre Louis Institute of Epidemiology and Public Health, Paris, France.
Pascal CrépeyUniv Rennes, EHESP, REPERES « Recherche en Pharmaco-Epidémiologie et Recours aux Soins »-EA 7449, 35043 Rennes, France.ORCID 0000-0003-1852-0752
Juliette PaireauMathematical Modelling of Infectious Diseases Unit, Institut Pasteur, UMR2000, CNRS, Paris, France.
Simon CauchemezMathematical Modelling of Infectious Diseases Unit, Institut Pasteur, UMR2000, CNRS, Paris, France.
François BeckSanté Publique France, French National Public Health Agency, Saint-Maurice, France.
Harold NoelSanté Publique France, French National Public Health Agency, Saint-Maurice, France.ORCID 0000-0003-3011-9267
Daniel Lévy-BruhlSanté Publique France, French National Public Health Agency, Saint-Maurice, France.
Vittoria ColizzaINSERM, Sorbonne Université, Pierre Louis Institute of Epidemiology and Public Health, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: After one year of stop-and-go COVID-19 mitigation, in the spring of 2021 European countries still experienced sustained viral circulation due to the Alpha variant. As the prospect of entering a new pandemic phase through vaccination was drawing closer, a key challenge remained on how to balance the efficacy of long-lasting interventions and their impact on the quality of life. Methods: Focusing on the third wave in France during spring 2021, we simulate intervention scenarios of varying intensity and duration, with potential waning of adherence over time, based on past mobility data and modeling estimates. We identify optimal strategies by balancing efficacy of interventions with a data-driven "distress" index, integrating intensity and duration of social distancing. Results: We show that moderate interventions would require a much longer time to achieve the same result as high intensity lockdowns, with the additional risk of deteriorating control as adherence wanes. Shorter strict lockdowns are largely more effective than longer moderate lockdowns, for similar intermediate distress and infringement on individual freedom. Conclusions: Our study shows that favoring milder interventions over more stringent short approaches on the basis of perceived acceptability could be detrimental in the long term, especially with waning adherence.

Indexed as

Computational biology and bioinformaticsInfectious diseasesPublic health

Identifiers

PMID35602184
PMCPMC9053235

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.