Evidence map›Paper›PMID 35602014›Full record

ArticleFrontiers in microbiology2022

Incorporating the Gut Microbiome in the Risk Assessment of Xenobiotics and Identifying Beneficial Components for One Health.

Antonis Ampatzoglou, Agnieszka Gruszecka-Kosowska, Alfonso Torres-Sánchez, Ana López-Moreno, Klara Cerk, Pilar Ortiz, Mercedes Monteoliva-Sánchez, Margarita Aguilera

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. AnFrontiers in immunology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Integration of Omics Approaches Enhances the Impact of Scientific Research in Environmental Applications.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antonis AmpatzoglouDepartment of Microbiology, Faculty of Pharmacy, University of Granada (UGR), Granada, Spain.
Agnieszka Gruszecka-KosowskaDepartment of Microbiology, Faculty of Pharmacy, University of Granada (UGR), Granada, Spain.
Alfonso Torres-SánchezDepartment of Microbiology, Faculty of Pharmacy, University of Granada (UGR), Granada, Spain.
Ana López-MorenoDepartment of Microbiology, Faculty of Pharmacy, University of Granada (UGR), Granada, Spain.
Klara CerkDepartment of Microbiology, Faculty of Pharmacy, University of Granada (UGR), Granada, Spain.
Pilar OrtizDepartment of Microbiology, Faculty of Pharmacy, University of Granada (UGR), Granada, Spain.
Mercedes Monteoliva-SánchezDepartment of Microbiology, Faculty of Pharmacy, University of Granada (UGR), Granada, Spain.
Margarita AguileraDepartment of Microbiology, Faculty of Pharmacy, University of Granada (UGR), Granada, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three areas of relevance to the gut microbiome in the context of One Health were explored; the incorporation of the microbiome in food safety risk assessment of xenobiotics; the identification and application of beneficial microbial components to various areas under One Health, and; specifically, in the context of antimicrobial resistance. Although challenging, focusing on the microbiota resilience, function and active components is critical for advancing the incorporation of microbiome data in the risk assessment of xenobiotics. Moreover, the human microbiota may be a promising source of beneficial components, with the potential to metabolize xenobiotics. These may have possible applications in several areas, e.g., in animals or plants for detoxification or in the environment for biodegradation. This approach would be of particular interest for antimicrobials, with the potential to ameliorate antimicrobial resistance development. Finally, the concept of resistance to xenobiotics in the context of the gut microbiome may deserve further investigation.

Indexed as

antimicrobial resistancegut microbiomemicrobiota disrupting chemicalsnext-generation probioticsnext-generation risk assessmentone healthxenobiotics

Identifiers

PMID35602014
PMCPMC9116292

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.