Evidence map›Paper›PMID 35602011›Full record

ArticleFrontiers in microbiology2022

Identifying the Novel Inhibitors Against the Mycolic Acid Biosynthesis Pathway Target "mtFabH" of

Niranjan Kumar, Rakesh Srivastava, Raj Kumar Mongre, Chandra Bhushan Mishra, Amit Kumar, Rosy Khatoon, Atanu Banerjee, Md Ashraf-Uz-Zaman, Harpreet Singh, Andrew M Lynn and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  4. Development ofMini reviews in medicinal chemistry · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Niranjan KumarSchool of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, India.
Rakesh SrivastavaSchool of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, India.
Raj Kumar MongreMolecular Cancer Biology Laboratory, Cellular Heterogeneity Research Center, Department of Biosystem, Sookmyung Women's University, Seoul, South Korea.
Chandra Bhushan MishraDepartment of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX, United States.
Amit KumarIndian Council of Medical Research-Computational Genomics Centre, All India Institute of Medical Research, New Delhi, India.
Rosy KhatoonAmity Institute of Biotechnology, Amity University, Gurugram, India.
Atanu BanerjeeAmity Institute of Biotechnology, Amity University, Gurugram, India.
Md Ashraf-Uz-ZamanDepartment of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX, United States.
Harpreet SinghIndian Council of Medical Research-Computational Genomics Centre, All India Institute of Medical Research, New Delhi, India.
Andrew M LynnSchool of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, India.
Myeong-Sok LeeMolecular Cancer Biology Laboratory, Cellular Heterogeneity Research Center, Department of Biosystem, Sookmyung Women's University, Seoul, South Korea.
Amresh PrakashAmity Institute of Integrative Sciences and Health, Amity University, Gurugram, India.
Jawaharlal Nehru University · INBaylor College of Medicine · USIndian Council of Medical Research · INSookmyung Women's University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycolic acids are the key constituents of mycobacterial cell wall, which protect the bacteria from antibiotic susceptibility, helping to subvert and escape from the host immune system. Thus, the enzymes involved in regulating and biosynthesis of mycolic acids can be explored as potential drug targets to kill

Indexed as

inhibitorMD simulationMM/PBSAmtFabHMycobacterium tuberculosismycolic acids

Identifiers

PMID35602011
PMCPMC9121832
OpenAlexW4229083951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.