Evidence map›Paper›PMID 35601974›Full record

ArticleNeuro-oncology practice2022

Primary central nervous system lymphoma: a real-world comparison of therapy access and outcomes by hospital setting.

Akshat M Patel, Omer Ali, Radhika Kainthla, Syed M Rizvi, Farrukh T Awan, Toral Patel, Edward Pan, Elizabeth Maher, Neil B Desai, Robert Timmerman and 2 more

Open access · greenAbstract read
In one paragraph

Article in Neuro-oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Akshat M PatelDivision of Hematologic Malignancies and Stem Cell Transplantation, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID https://orcid.org/0000-0002-8879-3046
Omer AliDivision of Hematologic Malignancies and Stem Cell Transplantation, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Radhika KainthlaDivision of Hematology/Oncology, Parkland Health and Hospital System, Dallas, Texas, USA.
Syed M RizviDivision of Hematologic Malignancies and Stem Cell Transplantation, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Farrukh T AwanDivision of Hematologic Malignancies and Stem Cell Transplantation, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Toral PatelDepartment of Neurosurgery, Parkland Health and Hospital System, Dallas, Texas, USA.
Edward PanDepartment of Neurology, Parkland Health and Hospital System, Dallas, Texas, USA.
Elizabeth MaherDepartment of Neurology, Parkland Health and Hospital System, Dallas, Texas, USA.
Neil B DesaiDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Robert TimmermanDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Kiran A KumarDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Praveen Ramakrishnan GeethakumariDivision of Hematologic Malignancies and Stem Cell Transplantation, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
The University of Texas Southwestern Medical Center · USParkland Health & Hospital System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study analyzes sociodemographic barriers for primary CNS lymphoma (PCNSL) treatment and outcomes at a public safety-net hospital versus a private tertiary academic institution. We hypothesized that these barriers would lead to access disparities and poorer outcomes in the safety-net population. Methods: We reviewed records of PCNSL patients from 2007-2020 ( Results: Patients at the safety-net hospital were significantly younger, more commonly Black or Hispanic, and had a higher prevalence of HIV/AIDS. They were significantly less likely to receive induction chemotherapy (67% vs 86%, Conclusions: Our study shows significant differences in treatment patterns for PCNSL between a public safety-net hospital and an academic cancer center. A significant survival difference was not demonstrated, which is likely multifactorial, but likely was positively impacted by the shared multidisciplinary care delivery between the institutions. As personalized therapies for PCNSL are being developed, equitable access including clinical trials should be advocated for resource-limited settings.

Indexed as

healthcare disparitieshealth services accessibilityoutcomespractice patternsprimary CNS lymphoma (PCNSL)

Identifiers

PMID35601974
PMCPMC9113306
OpenAlexW4226188756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.