Evidence map›Paper›PMID 35601926›Full record

ReviewJTO clinical and research reports2022

Implementing Lung Cancer Screening in Europe: Taking a Systems Approach.

Suzanne Wait, Arturo Alvarez-Rosete, Tasnime Osama, Dani Bancroft, Robin Cornelissen, Ante Marušić, Pilar Garrido, Mariusz Adamek, Jan van Meerbeeck, Annemiek Snoeckx and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in JTO clinical and research reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 3 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Risk prediction for lung cancer screening: a systematic review and meta-regression.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Guideline
  3. Lung Cancer Screening With Low-Dose Computed Tomography.Deutsches Arzteblatt international · 2023
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Progressive pulmonary fibrosis.European radiology · 2026
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 8 countries.

Suzanne WaitThe Health Policy Partnership, London, United Kingdom.
Arturo Alvarez-RoseteThe Health Policy Partnership, London, United Kingdom.
Tasnime OsamaThe Health Policy Partnership, London, United Kingdom.
Dani BancroftThe Health Policy Partnership, London, United Kingdom.
Robin CornelissenDepartment of Pulmonology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Ante MarušićDepartment of Radiology, University Hospital Centre Zagreb, Zagreb, Croatia.
Pilar GarridoMedical Oncology Department, Universidad de Alcalá, University Hospital Ramón y Cajal, Madrid, Spain.
Mariusz AdamekDepartment of Thoracic Surgery, Medical University of Silesia, Katowice, Poland.
Jan van MeerbeeckDepartment of Radiology, Antwerp University Hospital, Antwerp, Belgium.
Annemiek SnoeckxFaculty of Medicine and Health Sciences, Department of Radiology, University of Antwerp, Antwerp, Belgium.
Olivier LeleuDepartment of Pulmonology and Thoracic Oncology, Abbeville Hospital Centre, Abbeville, France.
Ebba Hallersjö HultVision Zero Cancer Innovation Milieu, coordinated by Stockholm School of Economics Institute for Research, Stockholm, Sweden.
Sébastien CouraudDepartment of Pulmonology and Thoracic Oncology, Lyon Sud Hospital, Lyon, France.
David R BaldwinRespiratory Medicine Unit, David Evans Centre, Nottingham City Hospital, Nottingham, United Kingdom.
Antwerp University Hospital · BECentre Hospitalier d'Albi · FRErasmus MC Cancer Institute · NLGdańsk Medical University · PLHôpital Lyon Sud · FRNottingham City Hospital · GBStockholm School of Economics · SEUniversidad de Alcalá · ESUniversity Hospital Centre Zagreb · HRUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the leading cause of cancer death in Europe. Screening by means of low-dose computed tomography (LDCT) can shift detection to an earlier stage and reduce lung cancer mortality in high-risk individuals. However, to date, Poland, Croatia, Italy, and Romania are the only European countries to commit to large-scale implementation of targeted LDCT screening. Using a health systems approach, this article evaluates key factors needed to enable the successful implementation of screening programs across Europe. Recent literature on LDCT screening was reviewed for 10 countries (Belgium, Croatia, France, Germany, Italy, the Netherlands, Poland, Spain, Sweden, and United Kingdom) and complemented by 17 semistructured interviews with local experts. Research findings were mapped against a health systems framework adapted for lung cancer screening. The European policy landscape is highly variable, but potential barriers to implementation are similar across countries and consistent with those reported for other cancer screening programs. While consistent quality and safety of screening must be ensured across all screening centers, system factors are also important. These include appropriate data infrastructure, targeted recruitment methods that ensure equity in participation, sufficient capacity and workforce training, full integration of screening with multidisciplinary care pathways, and smoking cessation programs. Stigma and underlying perceptions of lung cancer as a self-inflicted condition are also important considerations. Building on decades of implementation research, governments now have a unique opportunity to establish effective, efficient, and equitable lung cancer screening programs adapted to their health systems, curbing the impact of lung cancer on their populations.

Indexed as

Computed tomographyEarly detectionLung cancerPolicyScreening

Identifiers

PMID35601926
PMCPMC9121320
OpenAlexW4224216230

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.