Evidence map›Paper›PMID 35601892›Full record

ArticleMaterials today. Bio2022

Fusing spheroids to aligned μ-tissues in a heart-on-chip featuring oxygen sensing and electrical pacing capabilities.

Oliver Schneider, Alessia Moruzzi, Stefanie Fuchs, Alina Grobel, Henrike S Schulze, Torsten Mayr, Peter Loskill

Open access · goldAbstract read
In one paragraph

Article in Materials today. Bio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

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  9. Advanced Brain-on-a-Chip for Wetware Computing: A Review.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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  18. Multicellular 3D models to study myocardial ischemia-reperfusion injury.Frontiers in cell and developmental biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Oliver SchneiderFraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany.
Alessia MoruzziNMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.
Stefanie FuchsInstitute for Analytical Chemistry and Food Chemistry, Graz University of Technology, Graz, Austria.
Alina GrobelFraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany.
Henrike S SchulzeFraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany.
Torsten MayrInstitute for Analytical Chemistry and Food Chemistry, Graz University of Technology, Graz, Austria.
Peter LoskillNMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.
Fraunhofer Institute for Interfacial Engineering and Biotechnology · DEGraz University of Technology · ATNatural and Medical Sciences Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last decade, Organ-on-Chip (OoC) emerged as a promising technology for advanced

Indexed as

CMs, CardiomyocytesElectrical stimulationhiPSCs, human induced pluripotent stem cellsHoC, Heart-on-ChipMetabolismMicrophysiological systemsNoninvasive readoutsOoC, Organ-on-ChipOptical sensorsOrgan-on-Chip

Identifiers

PMID35601892
PMCPMC9120495
OpenAlexW4229074478

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.