Evidence map›Paper›PMID 35601761›Full record

ArticleHelminthologia2022

Autoimmunity in Human CE: Correlative with The Fertility Status of The CE Cyst.

E A El Saftawy, A Abdelraouf, M A Elsalam, P Zakareya, A Fouad, E A Albadawi, A H S Abobakr Ali, N M Amin

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Helminthologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

E A El SaftawyMedical Parasitology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
A AbdelraoufHBP Surgery Department NHTMRI. (National hepatology and tropical médecine Research Institute) Cairo, Egypt.
M A ElsalamEgyptian Fellowship of GIT & Hepatology, Nasser Institute for Research and Treatment, Cairo, Egypt.
P ZakareyaMaster's degree of clinical pathology, Ain Shames University, Cairo, Egypt.
A FouadClinical Pathology Department, National Hepatology And Tropical Medicine Research Institute, Cairo Egypt.
E A AlbadawiDepartment of Anatomy College of Medicine, Taibah University, Taibah KSA.
A H S Abobakr AliDepartment of Anatomy, Faculty of Minia University Minya Egypt.
N M AminMedical Parasitology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
National Water Research Center · EGAin Shams University · EGArmed Forces College of Medicine · EGCairo University · EGMinia University · EGNasser Institute hospital · EGTaibah University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic echinococcosis is speculated to exert several immune-evasion strategies involving autoimmune-phenomena. We evaluated the hypothesizes that the prevalence of autoantibodies increases in the sera of CE patients that may evidence the association between the parasite and autoimmune diseases. Sera from 63 subjects at distinct types of CE cyst fertility were investigated for antinuclear antibodies (ANA), and anti-CCP antibodies. Plasma levels and cellular production of IL-17A cytokine were specifically defined as being assumed to prime for autoimmunity. Healthy-controls were age and gender-matched to test sera. ANA expressions inside the surgically removed metacestode and adventitial layer were also assayed. Out of 63 patients, 35 % had fertile highly viable cysts (group-1), 41 % had fertile low viable cysts (group-2) and 24 % had non-fertile cysts (group-3). A four-fold increase in ANA sera-levels was detected in group-1 compared with their controls (

Indexed as

ANAanti-CCP antibodiesCEIL-17A

Identifiers

PMID35601761
PMCPMC9075880
OpenAlexW4225370490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.