Evidence map›Paper›PMID 35601684›Full record

ArticleChemistrySelect2022

Design, Synthesis, and Development of 4-[(7-Chloroquinoline-4-yl)amino]phenol as a Potential SARS-CoV-2 Mpro Inhibitor.

James Guevara-Pulido, Ronald A Jiménez, Sandra J Morantes, Deissy N Jaramillo, Paola Acosta-Guzmán

Open access · greenAbstract read
In one paragraph

Article in ChemistrySelect, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Multi-Component Synthesis of New Fluorinated-Pyrrolo[3,4-International journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Consensus Pharmacophore Strategy For Identifying Novel SARS-Cov-2 MJournal of chemical information and modeling · 2024
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

James Guevara-PulidoINQA Facultad de Ciencias Universidad El Bosque Bogotá Colombia.
Ronald A JiménezINQA Facultad de Ciencias Universidad El Bosque Bogotá Colombia.
Sandra J MorantesINQA Facultad de Ciencias Universidad El Bosque Bogotá Colombia.
Deissy N JaramilloINQA Facultad de Ciencias Universidad El Bosque Bogotá Colombia.
Paola Acosta-GuzmánINQA Facultad de Ciencias Universidad El Bosque Bogotá Colombia.
Universidad El Bosque · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of chloroquine analogs were designed to search for a less toxic chloroquine derivative as a potential SARS-CoV-2 Mpro inhibitor. Herein, an ANN-based QSAR model was built to predict the IC

Indexed as

ANNCytotoxicityIC50NanoparticlesVirtual Screening

Identifiers

PMID35601684
PMCPMC9111044
OpenAlexW4224227173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.