ArticleFrontiers in aging neuroscience2022
Beneficial Effect of High-Frequency Repetitive Transcranial Magnetic Stimulation for the Verbal Memory and Default Mode Network in Healthy Older Adults.
Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- Exploring cortical excitability modulation to promote cognitive resilience in aging: an rTMS study protocol.Frontiers in human neuroscience · 2026Article
- Voxel-based alterations in spontaneous brain activity among very-late-onset schizophrenia-like psychosis: A preliminary resting-state functional magnetic resonance imaging study.World journal of psychiatry · 2025Article
- Reduced Functional Connectivity in Nucleus Accumbens Subregions Associates With Cognitive Changes in Alzheimer's Disease.Brain and behavior · 2025Article
- Repetitive transcranial magnetic stimulation (rTMS) as a tool for cognitive enhancement in healthy adults: a review study.Medical & biological engineering & computing · 2024Review
- Efficacy and safety of repetitive Transcranial Magnetic Stimulation and transcranial Direct Current Stimulation in memory deficits in patients with Alzheimer's disease: Meta-analysis and systematic review.International journal of clinical and health psychology : IJCHPArticle
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
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Abstract
Repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral prefrontal cortex (DLPFC) is a non-invasive effective treatment for cognitive disorder, but its underlying mechanism of action remains unknown. The aim of this study was to explore the effect of a 2-week high-frequency (HF) active or sham 10 Hz rTMS on verbal memory in 40 healthy older adults. Resting-state functional magnetic resonance imaging (rs-fMRI) was used to measure functional connectivity (FC) within the default mode network (DMN). Verbal memory performance was evaluated using an auditory verbal learning test (AVLT). Additionally, we evaluated the relationship between memory improvement and FC changes within the DMN. The results revealed that HF-rTMS can enhance immediate recall and delayed recall of verbal memory and increased the FC of the bilateral precuneus (PCUN) within the DMN. The positive correlations between the immediate recall memory and the FC of the left PCUN after a 2-week intervention of HF-rTMS were detected. In conclusion, HF-rTMS may have the potential to improve verbal memory performance in older adults, which relation to FC changes in the DMN. The current findings are useful for increasing the understanding of the mechanisms of HF-rTMS, as well as guiding HF-rTMS treatment of cognitive disorders.
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