Evidence map›Paper›PMID 35601017›Full record

ArticleJournal of diabetes research2022

Characteristics and Clinical Significance of Intestinal Microbiota in Patients with Chronic Hepatitis B Cirrhosis and Type 2 Diabetes Mellitus.

Xiu Sun, Xin Chi, Yingying Zhao, Shunai Liu, Huichun Xing

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
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  5. Review
  6. Article
  7. S100A8/A9-activated IFNγCellular and molecular life sciences : CMLS · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xiu SunCenter of Liver Diseases Division 3, Beijing Ditan Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-6192-697X
Xin ChiCenter of Liver Diseases Division 3, Beijing Ditan Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-0301-5254
Yingying ZhaoCenter of Liver Diseases Division 3, Beijing Ditan Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-0213-3291
Shunai LiuNational Center for Infectious Diseases, Beijing, China.ORCID https://orcid.org/0000-0002-5688-8470
Huichun XingCenter of Liver Diseases Division 3, Beijing Ditan Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-9111-9669
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic hepatitis B cirrhosis is often accompanied by glucose metabolism disorder, and intestinal microbiota was closely related to both cirrhosis and diabetes. There are few studies on the role of intestinal microbiota in hepatitis B liver cirrhosis and diabetes mellitus (LCDM). The purpose of this study was to investigate the characteristics of intestinal microbiota in patients with LCDM and to evaluate the relationship between the severity of intestinal microbiota imbalance and clinical significance. Methods: A case-controlled study was conducted. People who met the inclusion and exclusion criteria of chronic HBV-related liver cirrhosis (LC), LCDM, and healthy controls (HC) were enrolled in, and their fecal and blood samples were collected. The V3-V4 region of 16s rDNA gene of fecal microbiota was sequenced; the bioinformatics analysis including Results: A total of 70 participants completed fecal and blood tests, including 20 HC, 20 LCDM, and 30 LC. The Conclusion: Intestinal microbiota of patients with LCDM was significantly disordered, and the degree was more serious than that cirrhosis patients without diabetes.

Indexed as

Diabetes Mellitus, Type 2Gastrointestinal MicrobiomeHepatitis B, ChronicDysbiosisEubacterialesFecesHumansLiver CirrhosisRNA, Ribosomal, 16SRNA, Ribosomal, 16S

Identifiers

PMID35601017
PMCPMC9122699
OpenAlexW4280499147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.