Evidence map›Paper›PMID 35600900›Full record

ReviewFrontiers in bioengineering and biotechnology2022

Hydrogels for Tissue Engineering: Addressing Key Design Needs Toward Clinical Translation.

Fei Xu, Chloe Dawson, Makenzie Lamb, Eva Mueller, Evan Stefanek, Mohsen Akbari, Todd Hoare

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Keratin-Laden Bioink for Corneal Stroma Bioprinting.Bioengineering (Basel, Switzerland) · 2026
    Article
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  18. Adaptive PEG Bis-dendron Hydrogels with Tunable Mechanics and Bioactivity.Chemistry of materials : a publication of the American Chemical Society · 2026
    Article
  19. Review
  20. Review

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fei XuDepartment of Chemical Engineering, McMaster University, Hamilton, ON, Canada.
Chloe DawsonDepartment of Chemical Engineering, McMaster University, Hamilton, ON, Canada.
Makenzie LambDepartment of Chemical Engineering, McMaster University, Hamilton, ON, Canada.
Eva MuellerDepartment of Chemical Engineering, McMaster University, Hamilton, ON, Canada.
Evan StefanekDepartment of Mechanical Engineering, University of Victoria, Victoria, BC, Canada.
Mohsen AkbariDepartment of Mechanical Engineering, University of Victoria, Victoria, BC, Canada.
Todd HoareDepartment of Chemical Engineering, McMaster University, Hamilton, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the soft mechanics and tunable cell interactions facilitated by hydrogels have attracted significant interest in the development of functional hydrogel-based tissue engineering scaffolds, translating the many positive results observed in the lab into the clinic remains a slow process. In this review, we address the key design criteria in terms of the materials, crosslinkers, and fabrication techniques useful for fabricating translationally-relevant tissue engineering hydrogels, with particular attention to three emerging fabrication techniques that enable simultaneous scaffold fabrication and cell loading: 3D printing,

Indexed as

BiomaterialsBioprintingElectrospinningHydrogelsTissue Engineering

Identifiers

PMID35600900
PMCPMC9119391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.