Evidence map›Paper›PMID 35600581›Full record

ArticleFrontiers in endocrinology2022

Low NAD

Mirella L Meyer-Ficca, Alexie E Zwerdling, Corey A Swanson, Abby G Tucker, Sierra A Lopez, Miles K Wandersee, Gina M Warner, Katie L Thompson, Claudia C S Chini, Haolin Chen and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Advances in immunological research on male infertility.Frontiers in reproductive health · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. NADTheranostics · 2024
    Article
  10. Review
  11. Sexually dimorphic effects of SARM1 deletion on cardiac NADAmerican journal of physiology. Heart and circulatory physiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Mirella L Meyer-FiccaSchool of Veterinary Medicine, Utah State University, Logan, UT, United States.
Alexie E ZwerdlingDepartment of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT, United States.
Corey A SwansonSchool of Veterinary Medicine, Utah State University, Logan, UT, United States.
Abby G TuckerDepartment of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT, United States.
Sierra A LopezSchool of Veterinary Medicine, Utah State University, Logan, UT, United States.
Miles K WanderseeSchool of Veterinary Medicine, Utah State University, Logan, UT, United States.
Gina M WarnerSignal Transduction and Molecular Nutrition Laboratory, Kogod Aging Center, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, MN, United States.
Katie L ThompsonSignal Transduction and Molecular Nutrition Laboratory, Kogod Aging Center, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, MN, United States.
Claudia C S ChiniSignal Transduction and Molecular Nutrition Laboratory, Kogod Aging Center, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, MN, United States.
Haolin ChenDepartment of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Eduardo N ChiniSignal Transduction and Molecular Nutrition Laboratory, Kogod Aging Center, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, MN, United States.
Ralph G MeyerSchool of Veterinary Medicine, Utah State University, Logan, UT, United States.
Utah State University · USMayo Clinic in Arizona · USJohns Hopkins University · USMayo Clinic in Florida · USWinnMed · US

Funding

Therapeutic implication of CD38 in CLLR01CA233790 · NCI · MAYO CLINIC JACKSONVILLE · PI CHINI, EDUARDO N · 2019 to 2023
$3.0M
Role of CD38 in NAD metabolism: from the basic biology of aging to translationR01AG058812 · NIA · MAYO CLINIC ROCHESTER · PI CHINI, EDUARDO N · 2018 to 2022
$2.0M
Molecular sensors for metabolic programming of the sperm epigenome and offspring physiologyR01HD103027 · NICHD · UTAH STATE UNIVERSITY · PI MEYER-FICCA, MIRELLA L · 2021 to 2025
$1.5M
NAD Metabolism in Male Reproductive AgingR56AG069745 · NIA · UTAH STATE UNIVERSITY · PI CHINI, EDUARDO N, MEYER-FICCA, MIRELLA L · 2020 to 2020
$381k
Vitamin B3 requirements of the TestisR15HD100970 · NICHD · UTAH STATE UNIVERSITY · PI MEYER, RALPH G · 2020 to 2020
$363k
NCI NIH HHS R01 CA233790NIA NIH HHS R01 AG058812NIA NIH HHS R56 AG069745NICHD NIH HHS R01 HD103027NICHD NIH HHS R15 HD100970
6 · The paper itself

Abstract

Advanced paternal age has increasingly been recognized as a risk factor for male fertility and progeny health. While underlying causes are not well understood, aging is associated with a continuous decline of blood and tissue NAD

Indexed as

NiacinAgingAnimalsMaleMiceMice, TransgenicNADSpermatogenesisNADNiacinagingmale fertilityniacinnicotinamideretinoic acidspermatogoniatestisvitamin B3

Identifiers

PMID35600581
PMCPMC9120959
OpenAlexW4229046528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.