Evidence map›Paper›PMID 35600553›Full record

ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2022

The developmental changes in intestinal epithelial cell proliferation, differentiation, and shedding in weaning piglets.

Min Wang, Lixia Wang, Xian Tan, Lei Wang, Xia Xiong, Yancan Wang, Qiye Wang, Huansheng Yang, Yulong Yin

Open access · goldAbstract read
In one paragraph

Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

  1. Porcine intestinal goblet cells: Guardians of mucosal immunity and barrier function.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
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  8. Supplementation with Potato Protein Concentrate andAnimals : an open access journal from MDPI · 2025
    Article
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  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Min WangHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, China.
Lixia WangHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, China.
Xian TanHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, China.
Lei WangHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, China.
Xia XiongHunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, Hunan, China.
Yancan WangHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, China.
Qiye WangHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, China.
Huansheng YangHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, China.
Yulong YinHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, China.
Hunan Normal University · CNInstitute of Subtropical Agriculture · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal epithelial homeostasis plays an important role in intestinal morphology and function. However, the developmental changes in intestinal epithelial cell turnover in piglets during early weaning are unknown so far. Thus, the aim of this work was to detect changes in piglet gut development from weaning to post-weaning d 14. Accordingly, 40 piglets were used in the present study, and 8 piglets were randomly selected for sampling at d 0, 1, 3, 7 and 14 post-weaning, respectively. The results showed that weaning stress significantly affected small intestinal morphological architecture, and this impact was the worst on d 3, and then returned to normal on d 14. Furthermore, the number of the marker of proliferation Ki-67 (Ki67) positive cells was decreased on d 1 and 3, and then recovered on d 14 (

Indexed as

DifferentiationIntestinal epithelial cellProliferationSheddingWeaning piglet

Identifiers

PMID35600553
PMCPMC9092860
OpenAlexW4206726912

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.