Evidence map›Paper›PMID 35600542›Full record

ReviewAnimal nutrition (Zhongguo xu mu shou yi xue hui)2022

Constraints on the utilization of cereal straw in lactating dairy cows: A review from the perspective of systems biology.

Bing Wang, Huizeng Sun, Diming Wang, Hongyun Liu, Jianxin Liu

Open access · goldAbstract readReview
In one paragraph

Review in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Enhancing the silage quality of Kangar (Veterinary and animal science · 2026
    Article
  2. Rice Epiphytic StrainAnimals : an open access journal from MDPI · 2026
    Article
  3. Effects of Substitution of Corn withAnimals : an open access journal from MDPI · 2026
    Article
  4. Article
  5. Review
  6. Influence of sugar beet (Frontiers in veterinary science · 2026
    Article
  7. The development of a silage-based biorefinery to deliver the maximum nutritional benefit for human consumption from UK grasslands.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. The potential ofFrontiers in microbiology · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bing WangInstitute of Dairy Science, MoE Key Laboratory of Molecular Animal Nutrition, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Huizeng SunInstitute of Dairy Science, MoE Key Laboratory of Molecular Animal Nutrition, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Diming WangInstitute of Dairy Science, MoE Key Laboratory of Molecular Animal Nutrition, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Hongyun LiuInstitute of Dairy Science, MoE Key Laboratory of Molecular Animal Nutrition, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Jianxin LiuInstitute of Dairy Science, MoE Key Laboratory of Molecular Animal Nutrition, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Zhejiang University · CNChina Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cereal straw, a human inedible crop byproduct, can be used as a roughage source in ruminants. However, the nutrition density and palatability are very low, limiting its efficient utilization in animal production. This review aims to systematically provide an overview of the limitations of cereal straws, which is crucial for developing new strategies to enhance the efficient use of cereal straws by lactating dairy cows. Evolutionary molecular biology makes it possible to comprehensively understand the limitations of using cereal straw as a roughage source in dairy cows by different techniques, e.g., multi-omics. Main constraints for utilization of cereal straw and stover in lactating dairy cows include low contents of easily fermented carbohydrates (pectin) and essential amino acids (Met, Phe, and branched-chain amino acids), high content of lignin and silica, and low nutrient digestibility. These cause insufficient supply of the precursors for milk synthesis and result in increased loss of nutrients in feces and urine. Several molecular mechanisms are revealed by multi-omics techniques, including changed amino acid and glucose metabolism, altered rumen microbial composition and function, and differential expression of miRNAs, mRNA, and protein in multi-organs that are associated with milk synthesis. These can be targets of approaches to improve the utilization of cereal straw by dairy cows. In addition, much attention should be given to the efficient countermeasures, including pretreatments by fibrolytic enzymes or steam explosion, dietary formulations such as supplement of pectin, methionine, and branched-chain amino acids, and feeding with other functional feedstuffs, which may improve the feeding and economic value of cereal straw for lactating dairy cows. The newly revealed functional genes (such as

Indexed as

Amino acid metabolismCereal strawGlucose utilizationMetabolitesRumen microbiome

Identifiers

PMID35600542
PMCPMC9097690
OpenAlexW4210706260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.