Evidence map›Paper›PMID 35600452›Full record

ReviewHeliyon2022

Liposomes: structure, composition, types, and clinical applications.

Hamdi Nsairat, Dima Khater, Usama Sayed, Fadwa Odeh, Abeer Al Bawab, Walhan Alshaer

Registry-linked trialAbstract readReview
In one paragraph

Review in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07401342 (An Assessment of the Efficacy and Safety of Employing a Duosomal Chemical Peel for Aesthetic Enhancement in the Periocular and Facial Regions), which is not on this map. Cited by 531 papers.

0numbers the graph read from it
0cells of the map it votes in
531citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07401342 phase4completednot on this mapstarted 2023, after this paper: background citation

An Assessment of the Efficacy and Safety of Employing a Duosomal Chemical Peel for Aesthetic Enhancement in the Periocular and Facial Regions

TypeinterventionalSponsorInstituto de Oftalmología Fundación Conde de ValencianaRan2023 to 2024Enrolled12ConditionsChemical PeelingArmsDuosomal chemical peel application
3 · Its place in the literature

Who cites it

531 citing papers in PubMed.

  1. Trial
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  3. Visualization of membrane-stabilized SorCS2Journal of structural biology: X · 2026
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471 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hamdi NsairatPharmacological and Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, 19328, Jordan.
Dima KhaterDepartment of Chemistry, Faculty of Arts and Science, Applied Science Private University, Amman, Jordan.
Usama SayedDepartment of Biology, The University of Jordan, Amman, 11942, Jordan.
Fadwa OdehDepartment of Chemistry, The University of Jordan, Amman, 11942, Jordan.
Abeer Al BawabDepartment of Chemistry, The University of Jordan, Amman, 11942, Jordan.
Walhan AlshaerCell Therapy Center, The University of Jordan, Amman, 11942, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liposomes are now considered the most commonly used nanocarriers for various potentially active hydrophobic and hydrophilic molecules due to their high biocompatibility, biodegradability, and low immunogenicity. Liposomes also proved to enhance drug solubility and controlled distribution, as well as their capacity for surface modifications for targeted, prolonged, and sustained release. Based on the composition, liposomes can be considered to have evolved from conventional, long-circulating, targeted, and immune-liposomes to stimuli-responsive and actively targeted liposomes. Many liposomal-based drug delivery systems are currently clinically approved to treat several diseases, such as cancer, fungal and viral infections; more liposomes have reached advanced phases in clinical trials. This review describes liposomes structure, composition, preparation methods, and clinical applications.

Indexed as

LamellarityLiposomesPhospholipidsStealth liposomesVaccinations

Identifiers

PMID35600452
PMCPMC9118483

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.