ArticleFrontiers in oncology2022
The Impact of Postoperative Tumor Burden on Patients With Brain Metastases.
Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Risk stratification for unfavorable outcome after resection of selected brain metastases in patients with multiple brain metastases.Journal of neuro-oncology · 2026Article
- Review
- Postoperative absence of residual intracranial tumor volume is associated with improved survival and intracranial disease control in non-small cell lung cancer brain metastases.Journal of neuro-oncology · 2025Article
- Complete resection of brain metastases - when does it matter?Journal of neuro-oncology · 2025Article
- Evaluating the Impact of Index Metastasis Resection in Patients with Multiple Brain Metastases.Cancers · 2025Article
- A prospective observational study of inflammatory mediators in cerebrospinal fluid after intraoperative radiotherapy of brain tumors.Therapeutic advances in medical oncology · 2025Article
- The Role of Repeated Surgical Resections for Recurrent Brain Metastases in Older Population.Medicina (Kaunas, Lithuania) · 2024Article
- Defining the role of surgery for patients with multiple brain metastases.Journal of neuro-oncology · 2024Article
- Navigating Brain Metastases: Unveiling the Potential of 3-Tesla Intraoperative Magnetic Resonance Imaging.Cancers · 2024Article
- Article
- Single brain metastases - prognostic factors and impact of residual tumor burden on overall survival.Frontiers in oncology · 2024Article
- Article
- Opportunities and Alternatives of Modern Radiation Oncology and Surgery for the Management of Resectable Brain Metastases.Cancers · 2023Review
- Neurosurgical Interventions for Cerebral Metastases of Solid Tumors.Deutsches Arzteblatt international · 2023Review
- Brain metastases in the elderly - Impact of residual tumor volume on overall survival.Frontiers in oncology · 2023Article
- Enhancing outcomes: neurosurgical resection in brain metastasis patients with poor Karnofsky performance score - a comprehensive survival analysis.Frontiers in oncology · 2023Article
- Low-Energy X-Ray Intraoperative Radiation Therapy (Lex-IORT) for Resected Brain Metastases: A Single-Institution Experience.Cancers · 2022Article
- Explainable machine learning/artificial intelligence model for estimating postoperative survival in renal cell carcinoma brain metastasis patients.Neuro-oncology advancesArticle
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14 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Brain metastases were considered to be well-defined lesions, but recent research points to infiltrating behavior. Impact of postoperative residual tumor burden (RTB) and extent of resection are still not defined enough. Patients and Methods: Adult patients with surgery of brain metastases between April 2007 and January 2020 were analyzed. Early postoperative MRI (<72 h) was used to segment RTB. Survival analysis was performed and cutoff values for RTB were revealed. Separate (subgroup) analyses regarding postoperative radiotherapy, age, and histopathological entities were performed. Results: A total of 704 patients were included. Complete cytoreduction was achieved in 487/704 (69.2%) patients, median preoperative tumor burden was 12.4 cm Conclusions: RTB is a strong predictor for survival. Maximal cytoreduction, as confirmed by postoperative MRI, should be achieved whenever possible, regardless of type of postoperative radiotherapy.
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