Evidence map›Paper›PMID 35600312›Full record

ReviewFrontiers in physiology2022

What is the Hidden Biological Mechanism Underlying the Possible SARS-CoV-2 Vertical Transmission? A Mini Review.

Rosa Sessa, Emanuela Anastasi, Gabriella Brandolino, Roberto Brunelli, Marisa Di Pietro, Simone Filardo, Luisa Masciullo, Gianluca Terrin, Maria Federica Viscardi, Maria Grazia Porpora

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. SARS-CoV-2 Infection in Pregnancy: Clues and Proof of Adverse Outcomes.International journal of environmental research and public health · 2023
    Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rosa SessaDepartment of Public Health and Infectious Diseases, Microbiology Section, Sapienza University of Rome, Rome, Italy.
Emanuela AnastasiDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Gabriella BrandolinoDepartment of Maternal and Child Health and Urology, Sapienza University of Rome, Rome, Italy.
Roberto BrunelliDepartment of Maternal and Child Health and Urology, Sapienza University of Rome, Rome, Italy.
Marisa Di PietroDepartment of Public Health and Infectious Diseases, Microbiology Section, Sapienza University of Rome, Rome, Italy.
Simone FilardoDepartment of Public Health and Infectious Diseases, Microbiology Section, Sapienza University of Rome, Rome, Italy.
Luisa MasciulloDepartment of Maternal and Child Health and Urology, Sapienza University of Rome, Rome, Italy.
Gianluca TerrinDepartment of Maternal and Child Health and Urology, Sapienza University of Rome, Rome, Italy.
Maria Federica ViscardiDepartment of Maternal and Child Health and Urology, Sapienza University of Rome, Rome, Italy.
Maria Grazia PorporaDepartment of Maternal and Child Health and Urology, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS- CoV-2) represents an emerging infection that is spreading around the world. Among susceptible patients, pregnant women are more likely to develop serious complications and negative obstetric outcomes. Vertical transmission constitutes a debating issue which has not been completely understood. This review aims at describing the currently available evidence on SARS-CoV2 vertical transmission. We carried out a computerized literature search in the Cochrane Library, PubMed, Scopus and Web of Science, selecting the most relevant studies on vertical transmission from the outbreak onset until February 2022. The analysis of the available literature identifies the presence of SARS-CoV2 genome in different biological specimens, confirming the hypothesis that a transplacental infection can occur. In spite of the high number of infected people around the world, mother-to-child infections have been infrequently reported but it can be observed under certain biologic conditions. A deep knowledge of the underlying mechanisms of SARS-CoV2 vertical transmission is of paramount importance for planning an adequate management for the affected mothers and newborns.

Indexed as

coronavirusneonatal infectionplacentapregnancypregnancy outcomesSARS-CoV-2vertical transmission

Identifiers

PMID35600312
PMCPMC9117645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.