Evidence map›Paper›PMID 35600184›Full record

ArticleAnnals of medicine and surgery (2012)2022

Effects of green synthesized zinc nanoparticles alone and along with albendazole against hydatid cyst protoscoleces.

Mojtaba Shakibaie, Amal Khudair Khalaf, Marziyeh Rashidipour, Hossein Mahmoudvand

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Article in Annals of medicine and surgery (2012), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Mojtaba ShakibaiePharmaceutical Sciences and Cosmetic Products Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Amal Khudair KhalafDepartment of Microbiology, College of Medicine, University of Thiqar, Iraq.
Marziyeh RashidipourRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Hossein MahmoudvandRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Lorestan University of Medical Sciences · IRKerman University of Medical Sciences · IRThi Qar University · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The current investigation aims to green synthesized the zinc nanoparticles (ZnNPs) using Methods: Different concentrations of the ZnNPs (50, 100, and 200 μg/ml) alone and combined with albendazole (ALZ, 100 μg/ml) were treated with hydatid cyst protoscoleces obtained from liver of infected sheep for 5-60 min Results: The size of green synthesized ZnNPs was ranged from 30 to 80 nm, most of these nanoparticles were between 50 and 60 nm in size. In vitro, the highest scolicidal effect of ZnNPs was observed at the concentration of 200 μg/ml, where it killed 81.6% of protoscolices. While the combination of these nanoparticles with ALZ, especially at the concentration of 200 μg/ml, completely killed the protoscolices after 10 min' exposure. However, compared to Conclusion: Based on the obtained results, ZnNPs particularly in combination with albendazole displayed the potent protoscolicidal

Indexed as

ApoptosisCaspase-3Cystic echinococcosisEx vivoIn vitroScolicidal

Identifiers

PMID35600184
PMCPMC9118496
OpenAlexW4280518043

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.